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Updated: Feb 15, 2026

Orthotopic Liver Transplantation in Rats
Published on: July 1, 2012
Perioperative Coagulation Management in Liver Transplant Recipients
Dmitri Bezinover1, Daniel Dirkmann2, James Findlay3
1Department of Anesthesia and Perioperative Medicine, Penn State University, Penn State College of Medicine, Hershey, PA.
Abstract:
We review contemporary coagulation management for patients undergoing liver transplantation. A better understanding of the complex physiologic changes that occur in patients with end-stage liver disease has resulted in significant advances in anesthetic and coagulation management. A group of internationally recognized experts have critically evaluated current approaches for coagulopathy detection and management. Strategies for blood component and factor replacement have been evaluated and recommended therapies proposed. Pharmacologic treatment and prevention of coagulopathy, management of patients receiving antiplatelet medications, and the role of transesophageal echocardiography for early detection and management of thromboses are presented.
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