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Identification of a noncanonical function for ribose-5-phosphate isomerase A promotes colorectal cancer formation by

Yu-Ting Chou1,2, Jeng-Kai Jiang3, Muh-Hwa Yang4

  • 1Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan.

Plos Biology
|January 17, 2018
PubMed
Summary

Ribose-5-phosphate isomerase A (RPIA) promotes colorectal cancer (CRC) by entering the nucleus to stabilize beta-catenin. This novel function of RPIA in CRC suggests its potential as a therapeutic target and prognostic biomarker.

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