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Related Experiment Videos

Systemic sclerosis and pregnancy complicated by obstructive uropathy.

M Moore, J E Saffran, H S Baraf

    American Journal of Obstetrics and Gynecology
    |December 15, 1985
    PubMed
    Summary

    Progressive systemic sclerosis complicated a twin pregnancy, causing obstructive uropathy due to a noncompliant abdominal wall. The case reviews pregnancy

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    Area of Science:

    • Rheumatology
    • Obstetrics
    • Nephrology

    Background:

    • Progressive systemic sclerosis (PSS) is a multisystem autoimmune disease characterized by fibrosis, vasculopathy, and autoantibodies.
    • Pregnancy in patients with PSS presents unique challenges due to potential maternal and fetal complications.
    • Obstructive uropathy can arise from various causes, including external compression or intrinsic renal pathology.

    Observation:

    • A patient with PSS experienced a twin pregnancy complicated by obstructive uropathy.
    • The noncompliant abdominal wall, a potential consequence of PSS, contributed to the uropathy.
    • The interplay between PSS and pregnancy necessitates careful management.

    Findings:

    • This case highlights a rare presentation of obstructive uropathy in pregnancy secondary to PSS-related abdominal wall changes.
    • The review discusses the bidirectional effects of PSS on pregnancy and vice versa.
    • Management strategies for PSS patients during pregnancy require a multidisciplinary approach.

    Implications:

    • Understanding the impact of PSS on pregnancy is crucial for optimizing maternal and fetal outcomes.
    • Early recognition and management of complications like obstructive uropathy are essential.
    • Further research into the pathophysiology and management of PSS in pregnancy is warranted.

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