Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

8.9K
Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
8.9K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

3.1K
3.1K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

2.7K
2.7K
Cooperative Binding of Transcription Regulators02:13

Cooperative Binding of Transcription Regulators

7.4K
Transcriptional regulators bind to specific cis-regulatory sequences in the DNA to regulate gene transcription. These cis-regulatory sequences are very short, usually less than ten nucleotide pairs in length. The short length means that there is a high probability of the exact same sequence randomly occurring throughout the genome.  Since regulators can also bind to groups of similar sequences, this further increases the chances of random binding. Transcriptional regulators form...
7.4K
Cooperative Binding of Transcription Regulators02:13

Cooperative Binding of Transcription Regulators

2.6K
2.6K
Machines01:19

Machines

584
Machines are complex structures consisting of movable, pin-connected multi-force members that work together to transmit forces. One example of a machine is the cutting plier, which is used to cut wires by applying forces to its handles. When equal and opposite forces are exerted on the handles of the cutting plier, they cause the cutting edges to come together and apply equal and opposite reaction forces on the wire, which are greater than the applied forces.
A free-body diagram of the...
584

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recognising and mitigating LLM Pollution in online behavioural research.

Nature communications·2026
Same author

A reporting checklist for large language models in behavioural science.

Nature human behaviour·2026
Same author

General scales unlock AI evaluation with explanatory and predictive power.

Nature·2026
Same author

The private solution trap in collective action problems across 34 nations.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

End of world beliefs are common, diverse, and predict how people perceive and respond to global risks.

Journal of personality and social psychology·2026
Same author

Detecting bias in algorithms used to disseminate information in social networks and mitigating it using multiobjective optimization.

PNAS nexus·2025
Same journal

Demonstration of a quantum C-NOT gate in a time-multiplexed fully reconfigurable photonic processor.

Nature communications·2026
Same journal

Nonlinear quantum light source with van der Waals ferroelectric NbOX<sub>2</sub> (X = Br, I).

Nature communications·2026
Same journal

Antagonistic histone H2A variants and autonomous heterochromatin formation shape epigenomic patterns in Arabidopsis.

Nature communications·2026
Same journal

The long tail of nitrate pollution in groundwater challenges governance of global water quality.

Nature communications·2026
Same journal

Select microbial metabolites promote tau aggregation in a murine tauopathy model.

Nature communications·2026
Same journal

Warming climate has lengthened global intense tropical cyclone seasons.

Nature communications·2026
See all related articles

Related Experiment Video

Updated: Feb 15, 2026

Constructing and Visualizing Models using Mime-based Machine-learning Framework
06:19

Constructing and Visualizing Models using Mime-based Machine-learning Framework

Published on: July 22, 2025

2.6K

Cooperating with machines.

Jacob W Crandall1, Mayada Oudah2, Tennom3

  • 1Computer Science Department, Brigham Young University, 3361 TMCB, Provo, UT, 84602, USA. crandall@cs.byu.edu.

Nature Communications
|January 18, 2018
PubMed
Summary
This summary is machine-generated.

This study introduces a new algorithm combining reinforcement learning with signaling mechanisms to achieve effective human-machine cooperation. The algorithm rivals human cooperation levels in complex games, demonstrating AI

More Related Videos

Ex Situ Normothermic Machine Perfusion of Donor Livers
12:13

Ex Situ Normothermic Machine Perfusion of Donor Livers

Published on: May 26, 2015

12.3K
Normothermic Ex Vivo Liver Machine Perfusion in Mouse
13:14

Normothermic Ex Vivo Liver Machine Perfusion in Mouse

Published on: September 25, 2023

4.3K

Related Experiment Videos

Last Updated: Feb 15, 2026

Constructing and Visualizing Models using Mime-based Machine-learning Framework
06:19

Constructing and Visualizing Models using Mime-based Machine-learning Framework

Published on: July 22, 2025

2.6K
Ex Situ Normothermic Machine Perfusion of Donor Livers
12:13

Ex Situ Normothermic Machine Perfusion of Donor Livers

Published on: May 26, 2015

12.3K
Normothermic Ex Vivo Liver Machine Perfusion in Mouse
13:14

Normothermic Ex Vivo Liver Machine Perfusion in Mouse

Published on: September 25, 2023

4.3K

Area of Science:

  • Artificial Intelligence
  • Human-Computer Interaction
  • Game Theory

Background:

  • Historically, AI progress is measured by defeating humans in games, neglecting cooperative scenarios.
  • Human-machine cooperation is complex, especially when preferences are not fully aligned or conflicting.
  • Cooperation relies on factors beyond computation, including intuition, emotions, and social cues.

Purpose of the Study:

  • To develop an algorithm capable of beneficial human-machine cooperation in non-trivial scenarios.
  • To explore the integration of reinforcement learning with signaling mechanisms for cooperative AI.

Main Methods:

  • Developed a novel algorithm combining a state-of-the-art reinforcement-learning approach.
  • Integrated mechanisms for signaling to facilitate communication and cooperation.
  • Tested the algorithm in various two-player repeated stochastic games.

Main Results:

  • The developed algorithm demonstrated successful cooperation with both humans and other algorithms.
  • Cooperation levels achieved by the algorithm were comparable to human cooperation.
  • Effectiveness was shown across a variety of stochastic game scenarios.

Conclusions:

  • General human-machine cooperation is achievable through a combination of reinforcement learning and signaling.
  • Simple algorithmic mechanisms can facilitate complex cooperative behaviors.
  • This work opens new avenues for AI systems that can effectively collaborate with humans.