Related Experiment Video

Updated: Feb 15, 2026

CRISPR-Cas9 Genome Editing of Rat Embryos using Adeno-Associated Virus AAV and 2-Cell Embryo Electroporation
08:24

CRISPR-Cas9 Genome Editing of Rat Embryos using Adeno-Associated Virus AAV and 2-Cell Embryo Electroporation

Published on: March 15, 2024

2.9K

Genome Stability Maintenance in Naked Mole-Rat

I O Petruseva1, A N Evdokimov1, O I Lavrik1,2,3

  • 1Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrentjeva Ave. 8, Novosibirsk, 630090, Russia.

Acta Naturae
|January 18, 2018
PubMed
Summary

Naked mole-rats exhibit remarkable longevity and cancer resistance due to superior DNA repair and unique aging mechanisms. Their cells resist senescence, offering insights into genome maintenance and aging processes.

Keywords:
DNA repairHeterocephalus glabercancer resistancegenome and proteome stability

More Related Videos

Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'08:31

Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'

Published on: May 26, 2013

11.5K
Covalent Binding of Antibodies to Cellulose Paper Discs and Their Applications in Naked-eye Colorimetric Immunoassays09:04

Covalent Binding of Antibodies to Cellulose Paper Discs and Their Applications in Naked-eye Colorimetric Immunoassays

Published on: October 21, 2016

15.2K

Related Concept Videos

Formula Mass and Mole Concepts of Compounds02:56

Formula Mass and Mole Concepts of Compounds

Formula Mass of Covalent Compounds
82.8K
Chemical Stoichiometry and Gases: Using Ideal Gas Law to Determine Moles03:12

Chemical Stoichiometry and Gases: Using Ideal Gas Law to Determine Moles

Chemical stoichiometry describes the quantitative relationships between reactants and products in chemical reactions.
30.1K
Mixtures of Gases: Dalton's Law of Partial Pressures and Mole Fractions03:03

Mixtures of Gases: Dalton's Law of Partial Pressures and Mole Fractions

Unless individual gases chemically react with each other, the individual gases in a mixture of gases do not affect each other’s pressure. Each gas in a mixture exerts the same pressure that it would exert if it were present alone in the container. The pressure exerted by each individual gas in a mixture is called its partial pressure.
44.4K
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
40.9K
Nuclear Stability03:18

Nuclear Stability

Protons and neutrons, collectively called nucleons, are packed together tightly in a nucleus. With a radius of about 10−15 meters, a nucleus is quite small compared to the radius of the entire atom, which is about 10−10 meters. Nuclei are extremely dense compared to bulk matter, averaging 1.8 × 1014 grams per cubic centimeter. If the earth’s density were equal to the average nuclear density, the earth’s radius would be only about 200 meters.
To hold positively charged protons together...
23.4K
RNA Stability01:53

RNA Stability

Intact DNA strands can be found in fossils, while scientists sometimes struggle to keep RNA intact under laboratory conditions. The structural variations between RNA and DNA underlie the differences in their stability and longevity. Because DNA is double-stranded, it is inherently more stable. The single-stranded structure of RNA is less stable but also more flexible and can form weak internal bonds. Additionally, most RNAs in the cell are relatively short, while DNA can be up to 250 million...
35.8K