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Role of micro-RNAs in breast cancer surgery
P McAnena1, A Lowery1, M J Kerin1
1Discipline of Surgery, Lambe Institute for Translational Research, School of Medicine, National University of Ireland, Galway, Ireland.
Background:
The management of breast cancer has changed dramatically in the molecular era. Micro-RNAs can contribute to multiple facets of cancer surgery.
Methods:
This narrative review, based on years of research on the role of micro-RNAs, focused on the potential of these small, robust RNAs to influence all aspects of breast cancer surgery.
Results:
Micro-RNAs have a potential role as biomarkers in the diagnosis, prognosis and evaluation of response to therapy in breast cancer. They may also contribute to future therapeutic strategies.
Conclusion:
The molecular era has changed understanding of cancer. Micro-RNAs have the potential for use in personalized cancer strategies.
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