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A decreasing function describes a relationship where the output consistently declines as the input increases. This means that for any two input values, if one is greater than the other, the corresponding output is smaller. Mathematically, a function f is decreasing on an interval I if for every x1 < x2​ in I, f (x1) > f (x2). This type of behavior is visually identified on a graph that slopes downward from left to right.The nature of a function can be analyzed by calculating...
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Protocols for Vaginal Inoculation and Sample Collection in the Experimental Mouse Model of Candida vaginitis
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Implementation of vaginal cleansing prior to cesarean delivery to decrease endometritis rates.

Laura Felder1, Amanda Paternostro1, Johanna Quist-Nelson2

  • 1a Department of Obstetrics and Gynecology , Sidney Kimmel Medical College of Thomas Jefferson University , Philadelphia , PA , USA.

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|January 19, 2018
PubMed
Summary
This summary is machine-generated.

Vaginal cleansing before cesarean delivery shows promise in reducing endometritis, a common postpartum complication. While implementation was not universal, the protocol led to a clinical decrease in infection rates.

Keywords:
Betadinecesarean deliveryendometritispregnancyvaginal cleansingvaginal preparation

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Disease Prevention
  • Surgical Site Infection Reduction

Background:

  • Endometritis is a frequent postpartum complication, particularly after cesarean delivery, leading to prolonged hospital stays and potential sepsis.
  • Precesarean vaginal preparation has demonstrated efficacy in reducing endometritis risk for patients in labor or with ruptured membranes.

Purpose of the Study:

  • To evaluate the practical implementation of a precesarean vaginal cleansing protocol.
  • To assess the impact of this protocol on postoperative endometritis rates in a clinical setting.

Main Methods:

  • A before-and-after retrospective cohort study design was employed.
  • The study evaluated the initial six months of protocol implementation at a single institution.
  • Primary outcome was implementation rate; secondary outcomes included endometritis and other postoperative complications.

Main Results:

  • The implementation rate reached 68.3% after six months (p < .001).
  • Postoperative endometritis rates decreased from 14.0% to 11.7% (p = .49), a clinical but not statistically significant reduction.
  • Rates of postoperative fever and infectious wound complications also showed non-significant decreases.

Conclusions:

  • Precesarean vaginal cleansing protocols show high initial uptake but are not universally adopted.
  • The protocol resulted in a clinical, though not statistically significant, reduction in postoperative endometritis.
  • Further research is necessary to optimize the uptake of this quality improvement measure.