Engineering precision biomaterials for personalized medicine
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Updated: Feb 15, 2026

Culture of Bladder Cancer Organoids as Precision Medicine Tools
Published on: December 28, 2021
Brian A Aguado1,2,3, Joseph C Grim1,2,3, Adrianne M Rosales1,2
1Department of Chemical and Biological Engineering, University of Colorado, Boulder, CO 80309, USA.
Abstract:
As the demand for precision medicine continues to rise, the "one-size-fits-all" approach to designing medical devices and therapies is becoming increasingly outdated. Biomaterials have considerable potential for transforming precision medicine, but individual patient complexity often necessitates integrating multiple functions into a single device to successfully tailor personalized therapies. Here, we introduce an engineering strategy based on unit operations to provide a unified vocabulary and contextual framework to aid the design of biomaterial-based devices and accelerate their translation.
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