Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Expression Occurs at Multiple Steps02:24

Regulation of Expression Occurs at Multiple Steps

26.6K
Gene expression can be regulated at almost every step from gene to protein. Transcription is the step that is most commonly regulated. This involves the binding of proteins to short regulatory sequences on the DNA. This association can either promote or inhibit the transcription of a gene associated with the respective sequence.
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
26.6K
Regulation of Expression Occurs at Multiple Steps02:24

Regulation of Expression Occurs at Multiple Steps

4.0K
4.0K
Predicting Molecular Geometry02:27

Predicting Molecular Geometry

46.2K
VSEPR Theory for Determination of Electron Pair Geometries
46.2K
Absolute and Local Extreme Values01:22

Absolute and Local Extreme Values

91
The highest and lowest values of a function, relative to a reference axis, are known as extreme values. These include absolute maximum and absolute minimum values, which represent the highest and lowest points the function reaches across its entire domain. Within a restricted portion of the function, the highest and lowest values are referred to as local maximum and local minimum values, respectively.Periodic functions, such as sine and cosine, show extreme values at infinitely many points due...
91
Errors occurring during blood pressure monitoring01:25

Errors occurring during blood pressure monitoring

1.5K
Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
1.5K
Prediction Intervals01:03

Prediction Intervals

3.4K
The interval estimate of any variable is known as the prediction interval. It helps decide if a point estimate is dependable.
However, the point estimate is most likely not the exact value of the population parameter, but close to it. After calculating point estimates, we construct interval estimates, called confidence intervals or prediction intervals. This prediction interval comprises a range of values unlike the point estimate and is a better predictor of the observed sample value, y. 
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantifying climate loss and damage consistent with a social cost of carbon.

Nature·2026
Same author

Valuing wildfire smoke-related mortality benefits from climate mitigation.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Quantifying the contributions of climate change and adaptation to mortality from unprecedented extreme heat events.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Wildfire smoke exposure and mortality burden in the USA under climate change.

Nature·2025
Same author

Susceptibility to Photosynthesis Suppression From Extreme Storms Is Highly Site-Dependent.

Global change biology·2025
Same author

Increasing Hydroclimatic Whiplash Can Amplify Wildfire Risk in a Warming Climate.

Global change biology·2025

Related Experiment Video

Updated: Feb 15, 2026

Synthesis and Microdiffraction at Extreme Pressures and Temperatures
07:26

Synthesis and Microdiffraction at Extreme Pressures and Temperatures

Published on: October 7, 2013

11.7K

Widespread persistent changes to temperature extremes occurred earlier than predicted.

Chao Li1,2, Yuanyuan Fang3, Ken Caldeira3

  • 1Department of Global Ecology, Carnegie Institution for Science, Stanford, California, USA. chaoli@uvic.ca.

Scientific Reports
|January 19, 2018
PubMed
Summary
This summary is machine-generated.

Persistent changes in temperature extremes are already evident globally, occurring earlier and more widely than climate models predict. These observed shifts are likely human-caused, suggesting future extreme events may happen sooner than anticipated.

More Related Videos

Intracerebroventricular Viral Injection of the Neonatal Mouse Brain for Persistent and Widespread Neuronal Transduction
10:15

Intracerebroventricular Viral Injection of the Neonatal Mouse Brain for Persistent and Widespread Neuronal Transduction

Published on: September 15, 2014

63.4K
Population and Single-Cell Analysis of Antibiotic Persistence in Escherichia coli
12:29

Population and Single-Cell Analysis of Antibiotic Persistence in Escherichia coli

Published on: March 24, 2023

2.8K

Related Experiment Videos

Last Updated: Feb 15, 2026

Synthesis and Microdiffraction at Extreme Pressures and Temperatures
07:26

Synthesis and Microdiffraction at Extreme Pressures and Temperatures

Published on: October 7, 2013

11.7K
Intracerebroventricular Viral Injection of the Neonatal Mouse Brain for Persistent and Widespread Neuronal Transduction
10:15

Intracerebroventricular Viral Injection of the Neonatal Mouse Brain for Persistent and Widespread Neuronal Transduction

Published on: September 15, 2014

63.4K
Population and Single-Cell Analysis of Antibiotic Persistence in Escherichia coli
12:29

Population and Single-Cell Analysis of Antibiotic Persistence in Escherichia coli

Published on: March 24, 2023

2.8K

Area of Science:

  • Climate Science
  • Extreme Weather Events
  • Climate Change Detection

Background:

  • Understanding the emergence of climate extremes from natural variability is crucial for climate adaptation and mitigation.
  • Identifying persistent changes in temperature extremes is key to assessing climate change impacts.

Purpose of the Study:

  • To provide observational evidence of persistent changes in temperature extremes.
  • To compare observed changes with climate model projections.
  • To investigate the drivers of observed changes.

Main Methods:

  • Analysis of observational data for temperature extremes.
  • Comparison with climate model simulations using historical natural and anthropogenic forcings.
  • Assessment of signal-to-noise ratios in observed and simulated data.

Main Results:

  • Persistent changes in temperature extremes have already emerged over large parts of the Earth.
  • Climate models underestimate the observed emergence of these changes, showing weaker signals and greater noise.
  • Observed changes are more likely anthropogenic than natural in origin.

Conclusions:

  • Observed changes in temperature extremes have occurred earlier and over a wider area than predicted by current climate models.
  • Model discrepancies are due to weaker simulated change and greater simulated variability.
  • Future temperature extremes may emerge sooner than projected, necessitating updated adaptation strategies.