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3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer
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New therapies in nonmuscle invasive bladder cancer treatment

Kareem N Rayn1, Graham R Hale1, Gustavo Pena-La Grave1

  • 1Urologic Oncology Branch, National Cancer Institute, NIH, Bethesda, MD, USA.

Indian Journal of Urology : IJU : Journal of the Urological Society of India
|January 19, 2018
PubMed
Abstract

Insights

Novel therapies for nonmuscle invasive bladder cancer (NMIBC) show promise in combating high recurrence and progression rates. Ongoing research and clinical trials are advancing treatment options for this challenging disease.

Area of Science:

  • Oncology
  • Urology
  • Cancer Research

Background:

  • Nonmuscle invasive bladder cancer (NMIBC) presents significant treatment challenges due to high recurrence and progression rates with existing therapies.
  • Recent advancements in technology and biological understanding are driving the development of new therapeutic agents for NMIBC.

Purpose of the Study:

  • To review current literature and ongoing clinical trials for novel therapies in nonmuscle invasive bladder cancer (NMIBC).

Main Methods:

  • A comprehensive literature review was conducted using PubMed.gov.
  • Active and recently completed clinical trials were identified through clinicaltrials.gov.

Main Results:

  • A diverse range of new therapies for NMIBC are under development.
  • These novel treatments leverage recent breakthroughs in immunotherapy and cancer biology.

Conclusions:

  • Current efforts to develop innovative therapeutic strategies for NMIBC are highly promising.
  • The field of NMIBC treatment is continuously evolving with new approaches.

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