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Related Experiment Videos

Reversible vertical ocular deviations associated with raised intracranial pressure.

L P Frohman, M J Kupersmith

    Journal of Clinical Neuro-Ophthalmology
    |September 1, 1985
    PubMed
    Summary

    Skew deviation typically indicates a brainstem lesion. However, this study shows that increased intracranial pressure can also cause skew deviation, even without structural brainstem abnormalities.

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    Area of Science:

    • Neuro-ophthalmology
    • Neurology
    • Brainstem Dysfunction

    Background:

    • Skew deviation is a common neuro-ophthalmologic sign often associated with brainstem lesions.
    • Posterior fossa abnormalities are frequently observed alongside skew deviation.

    Observation:

    • This study presents five cases of skew deviation in patients with elevated intracranial pressure.
    • These patients did not exhibit any structural lesions in the posterior fossa.

    Findings:

    • Increased intracranial pressure, independent of posterior fossa structural lesions, can induce skew deviation.
    • This suggests a mechanism involving secondary brainstem dysfunction due to elevated intracranial pressure.

    Implications:

    • Clinicians should consider elevated intracranial pressure as a potential cause of skew deviation.
    • This finding broadens the differential diagnosis for skew deviation, particularly in the absence of clear structural abnormalities.

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