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When the drugs don't work: treatment-resistant schizophrenia, serotonin and serendipity
Penelope Lowe1, Amir Krivoy2, Lilla Porffy3
1National Psychosis Service, South London and Maudsley NHS Foundation Trust, UK.
Therapeutic Advances in Psychopharmacology
|January 19, 2018
Abstract:
Treatment-resistant schizophrenia is a serious clinical problem. We adopt a systems-level approach positing a greater role for cognitive control mechanisms in the development of psychotic symptoms and illustrate the clinical application of this via a case report of treatment-resistant patients treated successfully with adjunct pro-cognitive serotonergic medication.