Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intrinsically Disordered Proteins02:18

Intrinsically Disordered Proteins

19.6K
Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
19.6K
Genetics of Speciation02:16

Genetics of Speciation

22.0K
Speciation is the evolutionary process resulting in the formation of new, distinct species—groups of reproductively isolated populations.
22.0K
What is Population Genetics?01:25

What is Population Genetics?

65.0K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
65.0K
What is Genetic Engineering?00:49

What is Genetic Engineering?

80.4K
Overview
80.4K
Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

9.3K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
9.3K
Types of Genetic Transfer Between Organisms02:18

Types of Genetic Transfer Between Organisms

31.2K
Genetic transfer occurs when genetic information is passed from one organism to another. It occurs via two mechanisms: vertical gene transfer and horizontal gene transfer. Vertical gene transfer occurs when genetic information is transferred from one generation to the next, which happens much more frequently than horizontal gene transfer. Both sexual and asexual reproduction are forms of vertical gene transfer, where one or more organisms pass some or all of their genome onto their progeny.
31.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Separation of Lignin from <i>Paulownia</i> and Its Application in DES Gels.

Gels (Basel, Switzerland)·2026
Same author

A Novel Polyacrylamide Composite Hydrogel Reinforced with Deep Eutectic Solvent-Pretreated <i>Paulownia</i> Cellulose/Nanocellulose: Preparation, Characterization and Properties.

Gels (Basel, Switzerland)·2026
Same author

Ananalysis of the effects of Treg cell therapy intervention on the gut microbiota of type 1 diabetic mice using 16S rRNA gene sequencing.

Experimental biology and medicine (Maywood, N.J.)·2026
Same author

<i>POLR3A</i>-related syndrome complicated with cerebral abscesses: a case report and literature review.

Frontiers in genetics·2026
Same author

NF1 with Multiple Cardiac Structural Abnormalities Leading to Cerebral Infarction.

Diagnostics (Basel, Switzerland)·2026
Same author

The first report of ceroid lipofuscinosis type 11 in China: a novel mutation of GRN and updated clinical review.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2025
Same journal

Unsupervised Clustering Identifies High-Risk Phenotypic Subgroup in Crescentic Glomerulonephritis Patients.

Kidney diseases (Basel, Switzerland)·2026
Same journal

Association of Body Composition-Related Indicators with Urinary Protein Levels and Proteinuria Remission in Patients with Primary Membranous Nephropathy.

Kidney diseases (Basel, Switzerland)·2026
Same journal

Development and Validation of a Multivariable Nomogram Predictive of Kidney Function after Cardiopulmonary Resuscitation.

Kidney diseases (Basel, Switzerland)·2026
Same journal

Telitacicept in IgA Nephropathy Patients with Severe Renal Impairment: A Case Series.

Kidney diseases (Basel, Switzerland)·2026
Same journal

Decade-Long Trends in Chronic Kidney Disease-Mineral and Bone Disorder Target Achievement and Mortality Associations among Chinese Hemodialysis Patients: Insights from the China DOPPS Study.

Kidney diseases (Basel, Switzerland)·2026
Same journal

Monthly versus Bimonthly Bioelectrical Impedance Analysis for Dry Weight Assessment and Intradialytic Hypotension: A Randomized Crossover Trial.

Kidney diseases (Basel, Switzerland)·2026
See all related articles

Related Experiment Video

Updated: Feb 15, 2026

Forward Genetic Approaches in Chlamydia trachomatis
09:03

Forward Genetic Approaches in Chlamydia trachomatis

Published on: October 23, 2013

13.3K

Genetics of Magnesium Disorders.

Heng Li1,2, Shiren Sun3, Jianghua Chen1

  • 1Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

Kidney Diseases (Basel, Switzerland)
|January 19, 2018
PubMed
Summary
This summary is machine-generated.

Magnesium homeostasis is crucial for cellular function and health. Studying rare genetic diseases has significantly advanced our understanding of kidney magnesium handling and dysmagnesemia management.

Keywords:
ClaudinsDysmagnesemiaIon channelsTRPM6Tight junction proteins

More Related Videos

Biodegradable Magnesium Stent Treatment of Saccular Aneurysms in a Rat Model - Introduction of the Surgical Technique
11:07

Biodegradable Magnesium Stent Treatment of Saccular Aneurysms in a Rat Model - Introduction of the Surgical Technique

Published on: October 1, 2017

11.6K
Mutagenesis and Analysis of Genetic Mutations in the GC-rich KISS1 Receptor Sequence Identified in Humans with Reproductive Disorders
12:49

Mutagenesis and Analysis of Genetic Mutations in the GC-rich KISS1 Receptor Sequence Identified in Humans with Reproductive Disorders

Published on: September 4, 2011

14.4K

Related Experiment Videos

Last Updated: Feb 15, 2026

Forward Genetic Approaches in Chlamydia trachomatis
09:03

Forward Genetic Approaches in Chlamydia trachomatis

Published on: October 23, 2013

13.3K
Biodegradable Magnesium Stent Treatment of Saccular Aneurysms in a Rat Model - Introduction of the Surgical Technique
11:07

Biodegradable Magnesium Stent Treatment of Saccular Aneurysms in a Rat Model - Introduction of the Surgical Technique

Published on: October 1, 2017

11.6K
Mutagenesis and Analysis of Genetic Mutations in the GC-rich KISS1 Receptor Sequence Identified in Humans with Reproductive Disorders
12:49

Mutagenesis and Analysis of Genetic Mutations in the GC-rich KISS1 Receptor Sequence Identified in Humans with Reproductive Disorders

Published on: September 4, 2011

14.4K

Area of Science:

  • Nephrology
  • Molecular Biology
  • Genetics

Background:

  • Magnesium (Mg2+) is a vital intracellular cation involved in numerous cellular processes.
  • Disruptions in magnesium levels (dysmagnesemia) are linked to various diseases and can be fatal.

Purpose of the Study:

  • To review magnesium homeostasis and function, focusing on renal handling.
  • To explore the roles of specific intrarenal channels and transporters in magnesium absorption.

Main Methods:

  • Review of literature on magnesium homeostasis and renal handling.
  • Analysis of genetic studies elucidating the molecular mechanisms of dysmagnesemia.
  • Discussion of key proteins involved in renal magnesium transport.

Main Results:

  • Rare genetic diseases have illuminated the complex regulatory network of kidney magnesium handling.
  • Identified key proteins include tight junction proteins (claudins), ion channels (TRPM6, ROMK), and regulatory proteins (ANK3, FXYD2).
  • Significant progress has been made in understanding renal magnesium transport pathways.

Conclusions:

  • Understanding genetic dysmagnesemia enhances knowledge of kidney magnesium regulation.
  • This knowledge aids in developing strategies for preventing and managing magnesium disorders.
  • Further research is essential to fully elucidate renal magnesium handling.