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Related Experiment Videos

'In-Situ Split' Liver Resection/ALPPS - Historical Development and Current Practice.

Hans J Schlitt1, Christina Hackl1, Sven Arke Lang1,2

  • 1Department of Surgery, University of Regensburg Medical Center, Regensburg, Germany.

Visceral Medicine
|January 19, 2018
PubMed
Summary
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In-situ split/associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a novel liver resection technique. Initially for specific cases, its use has rapidly expanded globally.

Area of Science:

  • Hepatobiliary Surgery
  • Surgical Oncology
  • Advanced Liver Resection Techniques

Background:

  • Extensive, multifocal, or critically located liver tumors often necessitate advanced resection methods.
  • The development of novel techniques is crucial for improving outcomes in complex liver surgeries.

Purpose of the Study:

  • To review the development and global dissemination of the in-situ split/associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) technique.
  • To analyze the evolution and application spectrum of this advanced liver resection method.

Main Methods:

  • Retrospective review of the initial cases and subsequent patient cohort at the index center.
  • Analysis of the technique's spread through Germany and worldwide following initial publications and communication.
Keywords:
ALPPSIn-situ splitIndicationLiver resectionTechnique

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Main Results:

  • The in-situ split/ALPPS technique was first developed intraoperatively in 2007 out of necessity.
  • Following successful initial applications, the method was deliberately used and subsequently spread rapidly worldwide.
  • Currently, the technique is applied to a broad range of indications by numerous hepatobiliary surgery centers.

Conclusions:

  • In-situ split/ALPPS is a recently developed liver resection technique initially intended for highly specific situations.
  • The technique has gained significant traction, leading to widespread adoption and application across various centers globally.