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[Cutaneous graft-versus-host disease].

A Cho1, U Just1, R Knobler2

  • 1Universitätsklinik für Dermatologie, Medizinische Universität Wien, Währinger Gürtel 18-20, 1090, Wien, Österreich.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|January 19, 2018
PubMed
Summary
This summary is machine-generated.

Graft-versus-host disease (GvHD) is a common complication after stem cell transplants, often affecting the skin. Early diagnosis and treatment by dermatologists are crucial for managing this complex condition.

Keywords:
Allogeneic stem cell transplantationExtracorporeal photopheresisLichenoidMultiorgan diseaseSclerotic

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Area of Science:

  • Dermatology
  • Hematology
  • Immunology

Background:

  • Graft-versus-host disease (GvHD) is a significant complication following allogeneic stem cell transplantation.
  • Cutaneous manifestations are the most frequent presentation of GvHD, highlighting the dermatologist's essential role.

Purpose of the Study:

  • To comprehensively review cutaneous GvHD types.
  • To present current therapeutic strategies for acute and chronic GvHD.
  • To aid clinicians in accurate diagnosis and treatment initiation.

Main Methods:

  • Expert recommendations based on clinical presentations.
  • Criteria for diagnosing cutaneous GvHD.

Main Results:

  • GvHD diagnosis can be challenging due to variable presentations.
  • Dermatologists play a critical role in identifying and managing skin GvHD.

Conclusions:

  • Accurate diagnosis and timely therapy are vital for optimal patient outcomes in GvHD.
  • Understanding diverse GvHD presentations is key for effective management.