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Updated: Feb 15, 2026

Perspectives on Neuroscience
Published on: July 31, 2007
The S phase: Beginning, middle, and end: A perspective
Heide L Ford1, Arthur B Pardee1
1Dana-Farber Cancer Institute, Boston, Massachusetts 02115-6084.
Abstract:
Events in the S phase of the cell cycle have been investigated to a relatively limited extent in comparison with those in G1 and M phases. Four aspects of S are briefly discussed in this report: (1) the final biochemical step permitting initiation of DNA synthesis, (2) determination of replication timing of individual genes and its mechanism, (3) S phase processes that lead to the onset of M phase, and (4) resetting the S-phase machinery. J. Cell. Biochem. Suppls. 30/31:1-7, 1998. © 1999 Wiley-Liss, Inc.
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