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Tissue engineering: The first decade and beyond.

Lawrence J Bonassar1, Charles A Vacanti1

  • 1Departments of Anesthesiology, Cell Biology and Biomedical Engineering, University of Massachusetts Medical School, Worcester, Massachusetts 01655.

Journal of Cellular Biochemistry
|January 19, 2018
PubMed
Summary
This summary is machine-generated.

Tissue engineering has advanced significantly over the past decade, focusing on biomaterials and cell integration for applications in orthopaedics and maxillofacial surgery. Future challenges involve integrating medicine, biology, and engineering for clinical translation.

Keywords:
biomaterialscell culturepolymerstissue engineeringtransplants

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Area of Science:

  • Biomaterials Science
  • Cell Biology
  • Regenerative Medicine

Background:

  • Tissue engineering has emerged as a critical field over the last decade.
  • Biomaterials research forms the foundation for tissue engineering advancements.

Purpose of the Study:

  • To review key developments in tissue engineering over the past 10 years.
  • To examine the role of biomaterials in tissue engineering.
  • To outline future challenges for clinical translation.

Main Methods:

  • Review of biomaterials research.
  • Analysis of early cell-material combination efforts.
  • Examination of current cell biology and materials science technologies.

Main Results:

  • Significant progress in biomaterials development for tissue engineering.
  • Successful applications demonstrated in orthopaedics and maxillofacial surgery.
  • Identification of key technologies in cell biology and materials science.

Conclusions:

  • Tissue engineering has matured, with biomaterials playing a foundational role.
  • Integration of diverse technologies is crucial for future clinical applications.
  • Continued interdisciplinary collaboration is essential for advancing the field.