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Apoptotic and Nonapoptotic Activities of Pterostilbene against Cancer

Rong-Jane Chen1, Hsiao-Che Kuo2, Li-Hsin Cheng3

  • 1Department of Food Safety/Hygiene and Risk Management, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan. janekhc@gmail.com.

International Journal of Molecular Sciences
|January 19, 2018
PubMed

Insights

Pterostilbene (PS) shows promise as an alternative cancer treatment, combating drug resistance and metastasis. This natural compound may be a valuable dietary supplement for cancer prevention and therapy.

Area of Science:

  • Oncology
  • Pharmacology
  • Nutritional Science

Background:

  • Cancer remains a leading cause of mortality worldwide.
  • Current cancer therapies can lead to drug resistance and metastatic recurrence, necessitating alternative strategies.
  • Pterostilbene (PS) is a natural compound with demonstrated anti-cancer properties.

Purpose of the Study:

  • To review the progression of tumors towards metastasis.
  • To summarize the anti-cancer activities of pterostilbene (PS).
  • To explore the potential clinical applications of PS as a novel cancer therapeutic.

Main Methods:

  • Literature review of tumor metastasis.
  • Systematic review of studies on pterostilbene's anti-cancer effects.
  • Analysis of current research on pterostilbene's pharmacological benefits.

Main Results:

  • Pterostilbene (PS) exhibits potent anti-cancer activities, including apoptosis induction.
  • PS demonstrates efficacy in preventing and treating various cancer stages.
  • Evidence suggests PS can counteract metastatic progression.

Conclusions:

  • Pterostilbene (PS) is a promising alternative medicine for cancer treatment.
  • PS can be utilized as a nutritional supplement for cancer prevention and therapy.
  • Further clinical research is warranted to establish PS as a standard therapeutic agent.
Keywords:
apoptosiscancer metastasisfibronectinpterostilbene

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