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Epidemiological investigation into the prevalence of abnormal inter-arm blood pressure differences among different
Ling Sun1, Ting Zou2, Bao-Zhu Wang1
1Department of Cardiology, First Affiliated Hospital of Xingjiang Medical University, Urumqi, China.
Insights
The prevalence of abnormal IAD was higher in Kazakhs compared to Han and Uygur populations in Xinjiang. Key risk factors for IAD include age, obesity, and triglyceride levels, with variations across ethnicities.
Area of Science:
- Cardiovascular Health
- Epidemiology
- Vascular Biology
Background:
- Inter-arm difference (IAD) prevalence and risk factors vary across ethnic groups.
- Understanding these variations is crucial for targeted cardiovascular risk assessment.
- Previous studies have not fully elucidated IAD epidemiology in Xinjiang's diverse ethnicities.
Purpose of the Study:
- To investigate the prevalence of abnormal IAD.
- To identify risk factors for IAD.
- To compare IAD prevalence and risk factors among Han, Uygur, and Kazakh populations in Xinjiang, China.
Main Methods:
- A cross-sectional study involving 14,618 adults using a 4-stage stratified cluster random sampling method.
- Data collection included questionnaires on personal information and medical history.
- IAD was diagnosed using a noninvasive arteriosclerosis analyzer.
Main Results:
- Overall abnormal IAD prevalence was 14.3%, with higher rates in Kazakh (16.4%) and Uygur (14.9%) compared to Han (12.5%) populations.
- Prevalence increased with age and was higher in hypertensive individuals across all groups.
- Significant risk factors included age >45, obesity, and hypertriglyceridemia; ethnic-specific factors were identified (e.g., smoking in Uygur, PAD in Kazakh).
Conclusions:
- Kazakh participants exhibited a higher prevalence of abnormal IAD than Han and Uygur populations.
- Age, obesity, and triglyceride levels are primary risk factors for IAD.
- Ethnic-specific risk factors necessitate tailored approaches for IAD management.
Objectives:
The prevalence of and risk factors for IAD among different ethnicity groups was unknown. Our aim was to investigate the prevalence of and risk factors for IAD among Han, Uygur and Kazakh ethnicities in Xinjiang. China.
Methods:
In total, 14,618 adult participants (7,799 males and 6,819 females) were recruited from the Cardiovascular Risk Survey. A 4-stage stratified cluster random sampling method was used. The participants' personal information and medical history were assessed by questionnaire. IAD was diagnosed by a noninvasive arteriosclerosis analyzer.
Results:
The prevalence of abnormal IAD among the general population was 14.3%, with 12.5% in the Han, 14.9% in the Uygur, and 16.4% in the Kazakh populations. The prevalence of abnormal IAD among the hypertensive population was 19.4%, with 17.0% in the Han, 18.1% in the Uygur, and 22.7% in the Kazakh populations. The prevalence of abnormal IAD increased with age (all P < 0.01) but was not significantly different between the genders (all P> 0.05). Multivariate logistic regression analysis showed that age more than 45 years, obesity and hypertriglyceridemia were significantly associated with a higher prevalence of IAD. There were different risk factors for abnormal IAD in different ethnicities. Middle or old age, obesity, ABI and diabetes mellitus were risk factors for the Han population, smoking was a risk factor in the Uygur population, and obesity and PAD were risk factors in the Kazakh population.
Conclusion:
The prevalence of abnormal IAD in the Kazakh participants was higher than that in the Han and Uygur populations among both the general population and the hypertensive population in Xinjiang, China. The main risk factors of IAD were age, obesity, and triglyceride levels. Different ethnicities had different kinds of risk factors for IAD.
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