Related Experiment Video
Updated: Feb 15, 2026

Porcine Model of Infrarenal Abdominal Aortic Aneurysm
Published on: November 21, 2019
Thoraco-abdominal aortic aneurysm rupture in a patient with Shprintzen-Goldberg syndrome
Naritaka Kimura1, Yu Inaba1, Kaori Kameyama2
1Department of Cardiovascular Surgery, Keio University School of Medicine, Tokyo, Japan.
Abstract:
Shprintzen-Goldberg syndrome is a rare systemic connective tissue disorder characterized by craniosynostosis, skeletal abnormalities, infantile hypotonia, mild-to-moderate intellectual disability and cardiovascular anomalies. To our knowledge, this is the first report of a Shprintzen-Goldberg syndrome patient who developed a thoraco-abdominal aortic aneurysm. The aneurysm grew rapidly necessitating emergent thoraco-abdominal aortic replacement. The postoperative course was uneventful, and a careful lifetime follow-up was planned.
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