Related Experiment Videos
Analgesic properties of enkephalinase inhibitors: animal and human studies
Progress in Clinical and Biological Research
|January 1, 1985
Abstract:
D-phenylalanine, bacitracin and puromycin produce long-lasting, naloxone-reversible analgesia in mice. Analgesic potency parallels potency of these compounds as inhibitors of met-enkephalin degradation by mouse brain enzymes. D-phenylalanine potentiates acupuncture analgesia in mice and humans and has been used to ameliorate a variety of human chronic pain conditions.