Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Polymers02:34

Polymers

41.5K
The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
41.5K
Polymers02:34

Polymers

23.4K
23.4K
Linear time-invariant Systems01:23

Linear time-invariant Systems

951
A system is linear if it displays the characteristics of homogeneity and additivity, together termed the superposition property. This principle is fundamental in all linear systems. Linear time-invariant (LTI) systems include systems with linear elements and constant parameters.
The input-output behavior of an LTI system can be fully defined by its response to an impulsive excitation at its input. Once this impulse response is known, the system's reaction to any other input can be...
951
pH Scale02:41

pH Scale

80.6K
Hydronium and hydroxide ions are present both in pure water and in all aqueous solutions, and their concentrations are inversely proportional as determined by the ion product of water (Kw). The concentrations of these ions in a solution are often critical determinants of the solution’s properties and the chemical behaviors of its other solutes. Two different solutions can differ in their hydronium or hydroxide ion concentrations by a million, billion, or even trillion times. A common means of...
80.6K
Rigid Body Equilibrium Problems - I00:49

Rigid Body Equilibrium Problems - I

5.5K
A rigid body is said to be in static equilibrium when the net force and the net torque acting on the system is equal to zero. To solve for rigid body equilibrium problems, do the following steps.
5.5K
Rigid Body Equilibrium Problems - II01:21

Rigid Body Equilibrium Problems - II

8.1K
A rigid body is in static equilibrium when the net force and the net torque acting on the system are equal to zero.
Consider two children sitting on a seesaw, which has negligible mass. The first child has a mass (m1) of 26 kg and sits at point A, which is 1.6 meters (r1) from the pivot point B; the second child has a mass (m2) of 32 kg and sits at point C. How far from the pivot point B should the second child sit (r2) to balance the seesaw?
8.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dynamics of driven translocation of semiflexible polymers.

Physical review. E·2018
Same author

Quantification of tension to explain bias dependence of driven polymer translocation dynamics.

Physical review. E·2018
Same author

Uniform description of polymer ejection dynamics from capsid with and without hydrodynamics.

Physical review. E·2017
Same author

Driven polymer translocation in good and bad solvent: Effects of hydrodynamics and tension propagation.

Physical review. E·2016
Same author

Chaperone-assisted translocation of flexible polymers in three dimensions.

Physical review. E·2016
Same author

Polymer ejection from strong spherical confinement.

Physical review. E, Statistical, nonlinear, and soft matter physics·2016
Same journal

Erratum: Low-dimensional model for adaptive networks of spiking neurons [Phys. Rev. E 111, 014422 (2025)].

Physical review. E·2026
Same journal

Disentangling the effects of many-body forces on depletion interactions.

Physical review. E·2026
Same journal

Charge transport and mode transition in dual-energy electron beam diodes.

Physical review. E·2026
Same journal

Optimization of multisite reactions in complex compartmentalized media.

Physical review. E·2026
Same journal

Origin of geometric cohesion in nonconvex granular materials: Interplay between interdigitation and rotational constraints enhancing frictional stability.

Physical review. E·2026
Same journal

Interaction of walkers with a standing Faraday wave.

Physical review. E·2026
See all related articles

Related Experiment Video

Updated: Feb 15, 2026

Author Spotlight: Exploring the Relationship Between Lipotoxicity and HFpEF
03:42

Author Spotlight: Exploring the Relationship Between Lipotoxicity and HFpEF

Published on: March 29, 2024

2.1K

Rigidity-induced scale invariance in polymer ejection from capsid.

R P Linna1, P M Suhonen1, J Piili1

  • 1Department of Computer Science, Aalto University, P.O. Box 15400, FI-00076 Aalto, Finland.

Physical Review. E
|January 20, 2018
PubMed
Summary
This summary is machine-generated.

Semiflexible polymer ejection from capsids differs from flexible polymers. Increased rigidity alters ejection dynamics, showing a crossover behavior similar to a phase transition.

More Related Videos

Alternative In Vitro Methods for the Determination of Viral Capsid Structural Integrity
12:57

Alternative In Vitro Methods for the Determination of Viral Capsid Structural Integrity

Published on: November 16, 2017

8.7K
Rigid Embedding of Fixed and Stained, Whole, Millimeter-Scale Specimens for Section-free 3D Histology by Micro-Computed Tomography
07:41

Rigid Embedding of Fixed and Stained, Whole, Millimeter-Scale Specimens for Section-free 3D Histology by Micro-Computed Tomography

Published on: October 17, 2018

9.4K

Related Experiment Videos

Last Updated: Feb 15, 2026

Author Spotlight: Exploring the Relationship Between Lipotoxicity and HFpEF
03:42

Author Spotlight: Exploring the Relationship Between Lipotoxicity and HFpEF

Published on: March 29, 2024

2.1K
Alternative In Vitro Methods for the Determination of Viral Capsid Structural Integrity
12:57

Alternative In Vitro Methods for the Determination of Viral Capsid Structural Integrity

Published on: November 16, 2017

8.7K
Rigid Embedding of Fixed and Stained, Whole, Millimeter-Scale Specimens for Section-free 3D Histology by Micro-Computed Tomography
07:41

Rigid Embedding of Fixed and Stained, Whole, Millimeter-Scale Specimens for Section-free 3D Histology by Micro-Computed Tomography

Published on: October 17, 2018

9.4K

Area of Science:

  • Biophysics
  • Polymer Physics
  • Computational Biology

Background:

  • The ejection dynamics of flexible polymers from viral capsids through nanopores are well-understood.
  • However, the behavior of semiflexible polymers under similar conditions remains largely uncharacterized.

Purpose of the Study:

  • To investigate and characterize the ejection dynamics of semiflexible polymers from spherical capsids using computational simulations.
  • To compare the ejection mechanisms of semiflexible polymers with those of fully flexible polymers.

Main Methods:

  • Molecular dynamics simulations were employed to model the ejection process.
  • Simulations focused on semiflexible polymers starting from confined conformations with constant initial monomer density.

Main Results:

  • Semiflexible polymer ejection force at the pore is not directly correlated with ejection velocity, unlike flexible polymers.
  • Cumulative monomer exit time (t(s)) shows a distinct change with increasing polymer rigidity (κ).
  • Ejection involves internal pressure-driven release followed by diffusion-controlled escape, with a crossover in dynamics for the driven portion.

Conclusions:

  • Increasing polymer rigidity (κ) induces a crossover in ejection dynamics, resembling a phase transition.
  • The study establishes a quantitative relationship for cumulative exit time: t(s)∝N₀⁰.⁵⁵s¹.³³ for rigid polymers.
  • A data collapse of exit times across different polymer lengths (N₀) and rigidities (κ) was observed, highlighting universal scaling behaviors.