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Updated: Feb 15, 2026
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In vitro Assessment of Cardiac Reprogramming by Measuring Cardiac Specific Calcium Flux with a GCaMP3 Reporter
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Primary cardiac angiosarcoma: A case report
Nóra Ambrus1, Kálmán Havasi1, Anita Kalapos1
1Faculty of Medicine, Second Department of Medicine and Cardiology Center, Albert Szent-Györgyi Clinical Centre, University of Szeged, Szeged, Hungary.
Echocardiography (Mount Kisco, N.Y.)
|January 20, 2018
Summary
Cardiac angiosarcomas, rare primary heart tumors, present with vague symptoms, delaying diagnosis. This case highlights the challenges in treating these aggressive tumors, with limited therapeutic options and poor prognosis.
Area of Science:
- Cardiology
- Oncology
- Pathology
Background:
- Cardiac angiosarcomas are the most frequent primary malignant tumors of the heart in adults.
- Diagnosis is frequently delayed due to nonspecific clinical presentations.
- Echocardiography and cardiac biopsy are essential diagnostic tools.
Observation:
- A 38-year-old woman presented with a primary heart tumor.
- The tumor infiltrated the right atrial wall and pericardium, leading to pericardial effusion.
- Histological evaluation confirmed angiosarcoma.
Findings:
- Surgical excision of the tumor was not radical.
- The patient's prognosis was poor, with survival of only 3 months post-diagnosis.
Implications:
- Treatment strategies for cardiac angiosarcoma remain controversial and limited.
- Outcomes for chemotherapy, radiotherapy, surgical removal, and heart transplantation require further investigation.
- This case underscores the aggressive nature and diagnostic challenges associated with cardiac angiosarcomas.
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