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Published on: September 22, 2015
Visible-light-induced multicomponent cascade cycloaddition involving N-propargyl aromatic amines, diaryliodonium
Deli Sun1, Kun Yin, Ronghua Zhang
1School of Chemical Science and Engineering, Tongji University, 1239 Siping Road, Shanghai 200092, China. rhzhang@tongji.edu.cn.
Abstract:
A visible-light-induced, Eosin Y catalyzed three-component synthesis of 3-arylsulfonylquinoline derivatives through N-propargyl aromatic amines, diaryliodonium salts and sulfur dioxide has been discovered. This transformation represents an efficient and attractive method for the straightforward synthesis of 3-arylsulfonylquinoline derivatives via the formation of C-S bonds and quinolines in one step. In addition, it exhibits good substrate scope and functional group tolerance. The use of easy-to-handle diaryliodonium salts, sulfur dioxide sources and the cheap photocatalyst Eosin Y together with facile operation at room temperature makes this protocol very practical.
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