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Published on: May 26, 2023
Microporous Luminescent Metal-Organic Framework for a Sensitive and Selective Fluorescence Sensing of Toxic Mycotoxin
Dan Tian1,2, Xiao-Jing Liu1, Rui Feng1
1School of Materials Science and Engineering, National Institute for Advanced Materials, TKL of Metal- and Molecule-Based Material Chemistry, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Nankai University , Tianjin 300350, P. R. China.
Abstract:
Food contamination by toxic mycotoxins not only causes a considerable loss in economy, but importantly poses a huge threat to human health through accidental ingestion. Hence, it is an ongoing and imperative need to develop a convenient, cost-effective method for the detection of the mycotoxin-infected agricultural commodities. To this end, we herein fabricated a novel metal-organic framework-derived composite material that displays a strong solid-state emission in the visible region, by attaching a frequently used fluorescent label, fluorescein isothiocyanate (FITC), via guest adsorption. Significantly, owing to the inherent pH-responsive conformational changes of FITC, the resulting composite material provides, to the best of our knowledge, the first example of the sensitive and selective fluorescence sensing toward 3-nitropropionic acid, which, as a major naturally occurring mycotoxin in moldy sugarcane, has been closely linked to poisoning episodes in human beings and animals.
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