Related Experiment Video
Updated: Feb 15, 2026

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
Published on: March 8, 2022
Melanoma in situ mimicking a Lichen planus-like keratosis
Andrea Sisti1, Amgiad Fallaha, Juri Tassinari
1General and Specialist Surgery Department, Plastic Surgery Division, University of Siena, Italy. asisti6@gmail.com.
Abstract:
The incidence of melanoma has steadily increased over the past three decades. Melanoma in situ (MIS), defined as melanoma that is limited to the epidermis, contributes to a disproportionately high percentage of this rising incidence. Amelanotic melanoma presents as an erythematous macule or plaque and may initially be misdiagnosed as an inflammatory disorder. We report a case of amelonatic MIS raised on non-sun-exposed skin, inducing a lichen planus-like keratosis as inflammatory reaction, which clinically masked the melanoma.
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