Related Experiment Video
Updated: Feb 15, 2026

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
Published on: June 28, 2024
Cleft-Palate Repair: Does Hospital Case-Volume Impact Outcomes or Cost?
Ari M Wes1,2, Daniel Mazzaferro1,2, Sanjay Naran1,2
1Philadelphia, Pa.
Insights
High-volume hospitals performing cleft palate repairs significantly reduce patient complications and prolonged hospital stays. This study highlights the importance of institutional experience for better surgical outcomes.
Area of Science:
- Health Services Research
- Surgical Outcomes
- Pediatric Surgery
Background:
- Hospital case volume significantly impacts operative outcomes and costs.
- Understanding the relationship between case volume and outcomes in cleft palate repair is crucial.
Purpose of the Study:
- To examine the association between cleft palate repair case volume and operative outcomes.
- To investigate the relationship between case volume and healthcare costs in cleft palate repair.
Main Methods:
- Retrospective analysis of over 20,000 patients undergoing cleft palate repair (2004-2015).
- Comparison of outcomes between high-volume and low-volume institutions.
- Primary outcomes included complications, prolonged length of stay, and total cost.
Main Results:
- High-volume centers showed lower rates of overall complications (3.4% vs 5.1%) and prolonged length of stay (4.5% vs 5.8%).
- Multivariate analysis confirmed reduced odds of complications (OR 0.678) and extended stay (OR 0.82) in high-volume centers.
- No significant difference in increased total cost was observed between high-volume and low-volume institutions (OR 1.01).
Conclusions:
- Institutions with high cleft palate repair volumes demonstrate significantly improved patient outcomes.
- High-volume centers are associated with decreased odds of complications and prolonged length of stay after cleft palate repair.
Background:
How hospital case-volume affects operative outcomes and cost continues to grow in importance. The purpose of this study was to examine the relationship of case volume with operative outcomes and cost in cleft palate repair.
Methods:
Subjects undergoing cleft palate repair between 2004 and 2015 were identified in the Pediatric Health Information System. Outcomes were compared between two groups: those undergoing treatment at a high-volume institution, and those undergoing treatment at a low-volume institution. Primary outcomes were as follows: any complication, prolonged length of stay, and increased total cost.
Results:
Over 20,000 patients (n = 20,320) from 49 institutions met inclusion criteria. On univariate analysis, those subjects who underwent treatment at a high-volume institution had a lower rate of overall complications (3.4 percent versus 5.1 percent; p < 0.001), and lower rates of prolonged length of stay (4.5 percent versus 5.8 percent; p < 0.001) and increased total cost (48.6 percent versus 50.9 percent; p = 0.002). In multivariate regression analyses, subjects treated in high-volume centers were less likely to experience any complication (OR, 0.678; p < 0.001) and were less likely to have an extended length of stay (OR, 0.82; p = 0.005). Subjects undergoing palate repair at a high-volume institution were no less likely to incur increased total cost (OR, 1.01; p = 0.805).
Conclusion:
In institutions performing a high volume of cleft palate repairs, subjects had significantly decreased odds of experiencing a complication or prolonged length of stay.
Clinical Question/Level Of Evidence:
Therapeutic, III.
Related Concept Videos
Hospitals-II
Nurses that work in...
Hospitals-I
Mismatch Repair
Overview of DNA Repair
Chemically...
Base Excision Repair
The first step of...
Nucleotide Excision Repair

