Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cerebral Hemispheres01:05

Cerebral Hemispheres

2.5K
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
2.5K
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

1.0K
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
1.0K
Regulation of Stroke Volume01:27

Regulation of Stroke Volume

5.3K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
5.3K
Cardiac Output and Stroke Volume01:11

Cardiac Output and Stroke Volume

5.0K
Cardiac output (CO) is an integral aspect of human physiology, reflecting the heart's efficiency and responsiveness to the body's needs. It represents the volume of blood that the left or right ventricle ejects into the aorta or pulmonary trunk each minute. The CO is calculated by multiplying the heart rate (HR)—the number of heartbeats per minute—by the stroke volume (SV)—the amount of blood pumped out with each heartbeat.
In an average resting adult male, the typical cardiac...
5.0K
Parallel Processing01:20

Parallel Processing

780
The brain processes sensory information rapidly due to parallel processing, which involves sending data across multiple neural pathways at the same time. This method allows the brain to manage various sensory qualities, such as shapes, colors, movements, and locations, all concurrently. For instance, when observing a forest landscape, the brain simultaneously processes the movement of leaves, the shapes of trees, the depth between them, and the various shades of green. This enables a quick and...
780
Information Processing Approach01:30

Information Processing Approach

610
The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
610

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management Challenges of Cerebral Venous Sinus Thrombosis With Hemorrhage in Congenital Dysfibrinogenemia.

Stroke·2026
Same author

Factors Related to Depression Symptoms in Chronic Poststroke Aphasia.

Archives of physical medicine and rehabilitation·2025
Same author

Full-head segmentation of MRI with abnormal brain anatomy: model and data release.

Journal of medical imaging (Bellingham, Wash.)·2025
Same author

Full-Head Segmentation of MRI with Abnormal Brain Anatomy: Model and Data Release.

ArXiv·2025
Same author

PerAF-based resting-state fMRI classifier for minimal hepatic encephalopathy.

Frontiers in neurology·2025
Same author

Adjunctive Human Urinary Kallidinogenase Enhances the Cognitive and Hemodynamic Outcomes of Anterior Circulation Stenting.

Translational stroke research·2025
Same journal

The cognitive construction of moral scenes: Associations of visuospatial ability and impulsivity with perspective and vividness in mental simulation.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

Theta band activity during event-file retrieval is influenced by stimulus salience in the preceding action episode.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

Language recovery in Hungarian speakers with aphasia: Roles of phonology and intraindividual variability.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

Neural and behavioral dissociations of self-focused and other-focused incentives in trust.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

A multiverse analysis of the logical memory test and plasma biomarkers of Alzheimer's disease.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same journal

Reading and writing impairments in Spanish-speaking individuals with primary progressive aphasia: A single-case series study.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
See all related articles

Related Experiment Video

Updated: Feb 15, 2026

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

3.8K

Phonotactic processing deficit following left-hemisphere stroke.

Maryam Ghaleh1, Laura M Skipper-Kallal1, Shihui Xing2

  • 1Georgetown University Medical Center, Neurology Department, Washington, DC, USA.

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
|January 21, 2018
PubMed
Summary
This summary is machine-generated.

This study reveals that damage to the left angular gyrus and posterior middle temporal gyrus impairs phonotactic knowledge, crucial for understanding speech sound combinations. This highlights key brain areas for processing language structure.

Keywords:
Left-hemisphere strokeLesion-symptom mappingPhonotacticsSublexical processingVoxel-based morphometry

More Related Videos

Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits
05:08

Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits

Published on: March 15, 2024

1.6K
The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies
10:45

The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies

Published on: February 7, 2025

1.6K

Related Experiment Videos

Last Updated: Feb 15, 2026

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

3.8K
Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits
05:08

Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits

Published on: March 15, 2024

1.6K
The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies
10:45

The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies

Published on: February 7, 2025

1.6K

Area of Science:

  • Neuroscience
  • Psycholinguistics
  • Speech Processing

Background:

  • The neural underpinnings of speech processing, particularly phonotactic knowledge, are not fully understood.
  • Phonotactic knowledge, the rules governing sound combinations in a language, is essential for fluent speech perception.

Purpose of the Study:

  • To identify brain regions critical for phonotactic knowledge in individuals with left-hemisphere stroke.
  • To compare these findings with gray matter anatomy related to phonotactic knowledge in healthy individuals.

Main Methods:

  • 44 left-hemisphere stroke survivors and 32 healthy controls rated the English-likeness of non-words.
  • Mixed effects modeling compared patient and control performance.
  • Multivariate lesion-symptom mapping and voxel-based morphometry identified key brain regions.

Main Results:

  • Stroke survivors showed reduced sensitivity to phonotactic regularities compared to controls.
  • Lesions in the left angular gyrus and posterior middle temporal gyrus correlated with decreased phonotactic sensitivity.
  • In controls, gray matter density in the left angular gyrus positively correlated with phonotactic sensitivity.

Conclusions:

  • The left angular gyrus and posterior middle temporal gyrus are crucial for phonotactic processing.
  • The angular gyrus may compare incoming speech to predictions based on stored lexical information in the posterior middle temporal gyrus.