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Hypovascular hypointense nodules in hepatobiliary phase without T2 hyperintensity: long-term outcomes and added value
Hae Jin Yang1, Ji Soo Song2, Eun Jung Choi2
1Department of Radiology, Chonbuk National University Medical School and Hospital, 20 Geonji-ro, Deokjin-gu, Jeonju, Chonbuk, 54907, Republic of Korea.
Purpose:
To evaluate outcomes and risk factors associated with hypervascularization in hypovascular, hepatobiliary phase (HBP) hypointense nodules (HHNs) without T2 hyperintensity on gadoxetic acid-enhanced magnetic resonance (MR) images in chronic liver disease patients.
Materials And Methods:
222 HHNs were analyzed. Multivariate analysis with a Cox proportional hazard regression model was used.
Results:
41 nodules became hypervascular hepatocellular carcinoma (HCC). History of HCC, hyperintensity on T1WI or DWI, and higher growth rate were risk factors for hypervascularization (P < .05).
Conclusion:
History of HCC, hyperintensity on T1WI or DWI, and higher growth rate were associated with nodular progression to hypervascular HCC.
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