[Quantitative coronary angiography before and after PTCA. Rate of restenosis, analysis of modifying factors]

In 95 consecutive patients in whom 101 coronary artery stenoses were successfully dilated, angiography was performed before, immediately after and at an average of 6.6 months after the procedures with computer-derived stenosis measurements (based on three-dimensional vessel reconstruction). The results were referenced to an analysis of factors possibly exerting an influence on post-PTCA outcome. In 56 of the 101 dilated stenoses (minimal area prior to PTCA 0.83 +/- 0.57 mm2, after PTCA 4.09 +/- 1.7 mm2), the findings remained essentially unchanged throughout the six-month follow-up. 17 of the 56 dilated stenoses showed a further increase in minimal area as compared with the findings seen immediately after PTCA. A reduction of the minimal area of more than 1 mm2 from that achieved immediately after PTCA, associated with narrowing of the vascular lumen greater than 70% was found in 33 of the 101 stenoses (minimal area before PTCA 0.82 +/- 0.59 mm2, immediately after PTCA 3.92 +/- 1.55 mm2, six months post-PTCA 1.39 +/- 1.27 mm2). In twelve of the 101 stenoses, restenosis amounting to more than 1 mm2 was also observed but without critical compromise of the vascular lumen (minimal area before PTCA 0.81 +/- 0.39 mm2, immediately after PTCA 5.54 +/- 1.28, six months post-PTCA 3.22 +/- 1.43 mm2, corresponding to a mean luminal narrowing of 45 +/- 24%).(ABSTRACT TRUNCATED AT 250 WORDS)