Related Experiment Video
Updated: Feb 15, 2026

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
Published on: February 6, 2020
Synthesis and self-assembly behavior of polyhedral oligomeric silsesquioxane-based triblock copolymers in selective
1School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China. xfwen@scut.edu.cn phpi@scut.edu.cn.
Abstract:
A polyhedral oligomeric silsesquioxane (POSS)-based hybrid triblock copolymer - methyl methacrylate-b-perfluoroalkylethyl methacrylate-b-methacrylisobutyl polyhedral oligomeric silsesquioxane (PMMA-b-PFMA-b-PMAPOSS) was synthesized via an atom transfer radical polymerization (ATRP) method. The self-assembly behavior of triblock copolymers in selective solvents of tetrahydrofuran (THF) and trichlorotrifluoroethane (F113) was studied using dissipative particle dynamics (DPD) simulation. The effects of the block sequence and volume ratio of F113/THF were discussed. The aggregate morphology and size were also characterized by transmission electron microscopy (TEM) and dynamic light scattering (DLS). The simulation results showed that the spherical micelle with core-shell-corona or core-mixed shell structure could be formed and the micelle size increased with the F113 content, which was in qualitative agreement with the experimental results. The DPD simulation revealed the dynamic process of the formation of aggregates at the mesoscopic scale, which can be considered as an adjunct to experiments and provides other valuable information for the experiments.
Related Concept Videos
Solvents
A...
Power Dissipated in a Circuit: Problem Solving
The simplest combinations of resistors are series and parallel connections. In a series circuit, the first resistor's output current flows into the second resistor's input; therefore, each resistor's current is the same. Thus, the equivalent resistance is the algebraic sum of the resistances. The current through the circuit can be found from Ohm's law and is equal to the...
Characteristics and Nomenclature of Copolymers
Titration in Nonaqueous Solvents
Protein Complex Assembly
Many viruses self-assemble into a fully functional unit using the infected host cell to...
Dehydration Synthesis
Dehydration synthesis (also called a condensation reaction) is the chemical process in which two molecules covalently link together to form a new molecule, along with the release of a water molecule. Many physiologically important compounds form by dehydration synthesis reactions, such as complex carbohydrates, proteins, DNA, and RNA.
Synthesis of carbohydrates
Sugar molecules are covalently linked together by dehydration synthesis. During the reaction, the hydroxyl (-OH) group from...

