Related Experiment Video
Updated: Feb 15, 2026

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
Published on: February 7, 2021
An injectable supramolecular hydrogel hybridized with silver nanoparticles for antibacterial application
Yanli Niu1, Tiantian Guo, Xiaoyan Yuan
1School of Materials Science and Engineering, and Tianjin Key Laboratory of Composite and Functional Materials, Tianjin University, Tianjin 300072, China. lxren@tju.edu.cn.
Abstract:
Silver nanoparticles (AgNPs) show long-lasting and broad-spectrum antibacterial activity. Herein, PEGylated AgNPs were prepared in situ by complexing AgNO3 with the random copolymer of poly(ethylene glycol) methyl ether methacrylate (PEGMA) and polyacrylic acid via electrostatic interaction followed by in situ reduction. AgNP hybrid supramolecular hydrogels were thus prepared through host-guest inclusion between PEGMA side chains and α-cyclodextrins in aqueous solution. The hydrogels were physically cross-linked by both pseudopolyrotaxane crystallization and AgNPs, which showed temperature responsiveness and self-healing properties. By hybridizing AgNPs, the hydrogels showed excellent antibacterial properties against S. aureus and E. coli bacteria as well as low cytotoxicity and have potential applications as injectable antibacterial materials.
More Related Videos
10:28An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
Published on: June 7, 2015
11:19Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
Published on: May 10, 2018
Related Concept Videos
Hybrid Zones
Hybridization of Atomic Orbitals I
Hybridization of Atomic Orbitals II
In-situ Hybridization
Types of probes and labels
A probe is a complementary strand of DNA or RNA that binds to corresponding nucleotide sequences in a cell. Many...
IR Absorption Frequency: Hybridization
Among the sp, sp2, and sp3 hybridized orbitals, sp orbitals have the maximum s character (50%). Consequently, the electrons are held more closely to the nucleus, resulting in stronger and shorter C–H bonds that...
Resonance and Hybrid Structures
Resonance Structures and Resonance Hybrids
The Lewis structure of a nitrite anion (NO2−) may actually be drawn in two different ways, distinguished by the locations of the N–O and N=O bonds.