Related Experiment Video
Updated: Feb 15, 2026

Focal Laser Ablation of Prostate Cancer: An Office Procedure
Published on: March 30, 2021
Comparison of laser ablation using multidirectional and forward-firing fibers in breast cancer
Jeeyeon Lee1, Jin Hyang Jung1, Wan Wook Kim1
1a Department of Surgery , Kyungpook National University School of Medicine , Daegu , Republic of Korea.
Background:
The aim of this study was to compare the therapeutic effect of laser ablation using the forward-firing fiber and the multidirectional-firing fiber for breast cancer treatment with pathologic results.
Material And Methods:
An ex vivo study of laser ablation was conducted using normal breast and breast cancer tissue. Each ablated area was demarcated into three zones, and the temperature was measured. Laser ablations using multidirectional and forward-firing types of fiber were compared regarding the shape, diameter and aspect ratio of the ablated lesions.
Results:
The ablated lesions were classified into three zones: a carbonized zone with complete tissue loss; a coagulated zone with no viable cells; and a non-damaged zone. The shape of the ablated lesion was elliptical using the forward-firing fiber and round using the multidirectional-firing fiber. Compared with normal breast tissue, breast cancer tissue required a more powerful setting for laser ablation to achieve necrosis, and the aspect ratio of the thermal lesion was higher for laser ablation using the multidirectional-firing fiber.
Conclusions:
The experimental results on breast tissue have shown that multidirectional-firing fiber is more effective than using forward-firing fibers and that this may prove to be another feasible therapeutic option for management of breast cancer.
More Related Videos
Related Concept Videos
The Sense of Self: Reflected Self-Appraisal and Social Comparison
Classification of Skeletal Muscle Fibers
Slow-Twitch Muscle Fibers
Slow oxidative, muscle fibers appear red due to large numbers of capillaries and high levels of...
Multiple Comparison Tests
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
Evolutionary Relationships through Genome Comparisons
Comparison Between Electrical And Gravitational Forces
Since both are inverse square law forces, the distance gets canceled when the ratio of the two forces is considered. Instead, the ratio of the electrical and gravitational forces depends on...
Comparison between RL and RC circuits

