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Continuous Glucose Monitoring in Healthy Children Aged 2-8 Years

Frida Sundberg1,2, Gun Forsander1,2

  • 11 Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg , Gothenburg, Sweden .

Diabetes Technology & Therapeutics
|January 23, 2018
PubMed

Insights

Continuous glucose monitoring (CGM) data from 15 healthy children aged 2-8 years provide essential reference ranges for pediatric diabetes research. These findings establish normal glycemic patterns in children, aiding future treatment outcome studies.

Area of Science:

  • Pediatric Endocrinology
  • Metabolic Research
  • Clinical Data Analysis

Background:

  • Establishing normative glycemic data in healthy children is crucial for interpreting glucose levels in pediatric diabetes.
  • Current understanding of daily glycemic patterns in young children lacks comprehensive data from continuous glucose monitoring (CGM).

Purpose of the Study:

  • To collect and present continuous glucose monitoring (CGM) data on glycemic levels and patterns in healthy children aged 2-8 years.
  • To provide essential reference data for research involving children with diabetes.

Main Methods:

  • A cohort of 15 healthy children (aged 2-7.99 years) participated in the study.
  • Each child wore a CGM device (Dexcom G4 Platinum) for a continuous period of 7 days.

Main Results:

  • The mean sensor glucose level across all participants was 5.3 ± 1.0 mmol/L (95 ± 18 mg/dL).
  • A significant majority of glucose values (89%) fell within the target range of 4-7.8 mmol/L (72-140 mg/dL).
  • Hypoglycemic events (<4.0 mmol/L) accounted for 9% of readings, while hyperglycemic events (>7.8 mmol/L) represented 2%.

Conclusions:

  • This study presents novel CGM-derived glycemic data for healthy children aged 2-8 years.
  • These findings establish a baseline for normal glycemic variability in this age group, valuable for clinical research.
Abstract

Keywords:
Continuous glucose monitoringHealthy childrenPreschool children.

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