Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

605
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
605
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

694
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
694
Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

422
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
422
Coordination Number and Geometry02:57

Coordination Number and Geometry

19.1K
For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar.
19.1K
Predicting Molecular Geometry02:27

Predicting Molecular Geometry

46.2K
VSEPR Theory for Determination of Electron Pair Geometries
46.2K
Geometry of Hyperbolas01:30

Geometry of Hyperbolas

531
A hyperbola consists of all points where the absolute difference of distances to two fixed points, called foci, remains constant. The standard equation isEach branch extends infinitely and approaches two asymptotes, which guide the curve’s behavior. The parameters a and b define key features: a measures the distance from the center to each vertex along the transverse axis, while b influences the slopes of the asymptotes. The asymptotes have equationsA rectangle centered at the origin with...
531

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tissue removal inside the beating heart using a robotically delivered metal MEMS tool.

The International journal of robotics research·2026
Same author

Midterm results of Ozaki technique for aortic valve reconstruction comparing autologous and bovine pericardium in congenital aortic valve disease.

JTCVS structural and endovascular·2026
Same author

Evaluation of neo-innominate connection in bilateral bidirectional Glenn patients using computational flow modeling.

JTCVS structural and endovascular·2026
Same author

Myocardial protection during cardiac surgery: Scientific principles and practical recommendations.

JTCVS structural and endovascular·2026
Same author

Numerical Analysis of Blood Flow Dynamics in Pediatric ECMO Circuits.

Annals of biomedical engineering·2026
Same author

Pathology of explanted novel expanded polytetrafluoroethylene pulmonary valved conduits reveals paucity of leaflet tissue response but frequent nonadherent thrombus formation.

The Journal of thoracic and cardiovascular surgery·2026
Same journal

Adaptive Admittance Control for Robotic Ultrasound Examination Based on a Breast Biomechanical Model.

The international journal of medical robotics + computer assisted surgery : MRCAS·2026
Same journal

Robotic Choledochal Cyst Excision With Intracorporeal Roux-en-Y Hepaticojejunostomy in Adolescent and Adult Patients: Clinical and Quality-of-Life Outcomes.

The international journal of medical robotics + computer assisted surgery : MRCAS·2026
Same journal

Short-Term Outcomes and Quality of Life After Robotic Versus Laparoscopic Double-Flap Technique for Proximal Gastrectomy: A Retrospective Cohort Study.

The international journal of medical robotics + computer assisted surgery : MRCAS·2026
Same journal

Dual-Modal Safety Framework for Robotic-Assisted Bronchoscopy via Endoscopic Vision and Haptic Feedback.

The international journal of medical robotics + computer assisted surgery : MRCAS·2026
Same journal

Soft Robots for Intestinal Applications: A Review on Actuation, Materials, Manufacture and Applications.

The international journal of medical robotics + computer assisted surgery : MRCAS·2026
Same journal

Robot-Assisted Thoracic Surgery Versus Video-Assisted Thoracic Surgery for Lung Resection: A Systematic Review and Meta-Analysis.

The international journal of medical robotics + computer assisted surgery : MRCAS·2026
See all related articles

Related Experiment Video

Updated: Feb 15, 2026

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
07:42

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

Published on: May 19, 2020

7.6K

Fast image-based mitral valve simulation from individualized geometry.

Pierre-Frederic Villard1,2, Peter E Hammer2,3, Douglas P Perrin2,3

  • 1LORIA, University of Lorraine, Inria, Nancy, France.

The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS
|January 23, 2018
PubMed
Summary
This summary is machine-generated.

This study presents a computational model to simulate mitral valve function, aiding surgeons in predicting surgical outcomes for valve repair. The model accurately predicts leaflet closure and identifies key chordae tendineae roles.

Keywords:
FEM simulationimage-based modelmitral valve modelvalidation metrics

More Related Videos

Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve
09:13

Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve

Published on: June 14, 2017

13.5K
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

2.5K

Related Experiment Videos

Last Updated: Feb 15, 2026

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
07:42

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

Published on: May 19, 2020

7.6K
Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve
09:13

Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve

Published on: June 14, 2017

13.5K
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

2.5K

Area of Science:

  • Computational modeling and simulation
  • Biomechanical engineering
  • Medical imaging analysis

Background:

  • Mitral valve surgery often involves chordae tendineae modification for prolapse.
  • Predicting mitral valve competence post-surgery is crucial for patient outcomes.
  • Biomechanical modeling offers a potential solution for pre-operative assessment.

Purpose of the Study:

  • To develop a semi-automatic method for creating patient-specific computational mitral valve models.
  • To simulate mitral valve leaflet closure at peak systole using finite element analysis.
  • To establish metrics for evaluating simulation accuracy and identifying influential chordae tendineae.

Main Methods:

  • Semi-automatic computational model generation from micro CT scans.
  • Finite element method (FEM) simulation using Simulation Open Framework Architecture (SOFA).
  • Validation using three metrics: point-to-surface error, coaptation area, and leak assessment.

Main Results:

  • The model accurately predicted closed valve geometry (approx. 1mm error).
  • Simulations showed a reasonable coaptation surface area and no leakage at peak systole.
  • Marginal chordae tendineae were found to have a greater influence on valve shape than intermediate ones.

Conclusions:

  • Mitral valve simulation provides valuable insights into valve mechanics.
  • This approach can assist surgeons in anticipating procedural outcomes.
  • The developed model aids in understanding the role of individual chordae tendineae.