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Updated: Feb 15, 2026

Preparation of Mouse Retinal Cryo-sections for Immunohistochemistry
Published on: July 1, 2019
Tubercular retinal vasculitis mimicking frosted branch angiitis: a case report
Manisha Agarwal1, Ankita Shrivastav2, Abdul Waris3
1Dr. Shroff's Charity Eye Hospital, 5027, Kedarnath Road, Daryaganj, New Delhi, 110002, India. agarwalmannii@yahoo.co.in.
Background:
Tubercular vasculitis is an important manifestation of ocular tuberculosis and this report highlights the mimicking nature of the disease with frosted branch angiitis.
Results:
A patient presented with a severe form of retinal vasculitis in both eyes and a branch retinal vein occlusion in the left eye. He had a positive tuberculin skin test (TST) and a raised erythrocyte sedimentation rate (ESR) and serum angiotensin-converting enzyme (ACE) levels. Radiological investigations revealed a sub-pleural nodule and mediastinal lymph nodes, which on histopathological evaluation confirmed a granulomatous etiology.
Conclusion:
Retinal vasculitis secondary to tubercular etiology may mimic a viral vasculitis; however, a clinical suspicion with a timely diagnosis and management helps in preventing loss of vision and the eye.
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