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Application of stacked convolutional and long short-term memory network for accurate identification of CAD ECG
Jen Hong Tan1, Yuki Hagiwara1, Winnie Pang1
1Department of Electronics and Computer Engineering, Ngee Ann Polytechnic, Singapore.
Insights
This study introduces a deep learning model combining Long Short-Term Memory (LSTM) and Convolutional Neural Networks (CNN) for accurate automated diagnosis of Coronary Artery Disease (CAD) using electrocardiogram (ECG) signals, achieving 99.85% accuracy.
Area of Science:
- Cardiology
- Artificial Intelligence
- Biomedical Engineering
Background:
- Coronary Artery Disease (CAD) is a leading global cause of heart disease, often asymptomatic in early stages.
- Electrocardiogram (ECG) is a common diagnostic tool for CAD but suffers from low sensitivity due to challenges in interpreting low-amplitude signals.
- Manual interpretation of ECGs can be error-prone, necessitating automated diagnostic solutions.
Purpose of the Study:
- To develop and implement a deep learning model for automated and objective interpretation of ECG signals for CAD diagnosis.
- To enhance the diagnostic accuracy and reliability of CAD detection from ECG data.
Main Methods:
- Implementation of a hybrid deep learning architecture integrating Long Short-Term Memory (LSTM) networks and Convolutional Neural Networks (CNN).
- Training and validation of the model on ECG signals to identify patterns indicative of CAD.
- Utilizing a blindfold strategy to evaluate the model's diagnostic performance.
Main Results:
- The proposed LSTM-CNN model achieved a high diagnostic accuracy of 99.85% in detecting CAD from ECG signals.
- The model demonstrates significant potential for accurate and automated CAD diagnosis.
Conclusions:
- The developed deep learning model offers a promising approach for accurate automated CAD diagnosis using ECGs.
- The prototype is ready for further validation with large-scale clinical databases before potential deployment.
Abstract:
Coronary artery disease (CAD) is the most common cause of heart disease globally. This is because there is no symptom exhibited in its initial phase until the disease progresses to an advanced stage. The electrocardiogram (ECG) is a widely accessible diagnostic tool to diagnose CAD that captures abnormal activity of the heart. However, it lacks diagnostic sensitivity. One reason is that, it is very challenging to visually interpret the ECG signal due to its very low amplitude. Hence, identification of abnormal ECG morphology by clinicians may be prone to error. Thus, it is essential to develop a software which can provide an automated and objective interpretation of the ECG signal. This paper proposes the implementation of long short-term memory (LSTM) network with convolutional neural network (CNN) to automatically diagnose CAD ECG signals accurately. Our proposed deep learning model is able to detect CAD ECG signals with a diagnostic accuracy of 99.85% with blindfold strategy. The developed prototype model is ready to be tested with an appropriate huge database before the clinical usage.
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