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Stricturing Crohn's disease-like colitis in a patient treated with belatacept
Anne Bozon1, Guillaume Jeantet2, Benjamin Rivière3
1Gastroenterology Department, Saint-Eloi Hospital, Montpellier University Hospital, Montpellier 34000, France.
World Journal of Gastroenterology
|January 24, 2018
Abstract:
Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) modifying agents have been involved in the development of intestinal inflammation, especially therapeutic monoclonal antibodies directed against CTLA-4. Here we report the appearance of a severe stricturing Crohn's disease-like colitis in a patient with a kidney allograft who was treated with belatacept, a recombinant CTLA-4-Ig fusion protein.