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Updated: Feb 15, 2026

Measurement of Particle Size Distribution in Turbid Solutions by Dynamic Light Scattering Microscopy
Published on: January 9, 2017
Correction of an adding-doubling inversion algorithm for the measurement of the optical parameters of turbid media
Paul Lemaillet1, Catherine C Cooksey1, Jeeseong Hwang2
1National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, MD 20899, USA.
Abstract:
We present broadband measurements of the optical properties of tissue-mimicking solid phantoms using a single integrating sphere to measure the hemispherical reflectance and transmittance under a direct illumination at the normal incident angle. These measurements are traceable to reflectance and transmittance scales. An inversion routine using the output of the adding-doubling algorithm restricted to the reflectance and transmittance under a direct illumination was developed to produce the optical parameters of the sample along with an uncertainty budget at each wavelength. The results for two types of phantoms are compared to measurements by time-resolved approaches. The results between our method and these independent measurements agree within the estimated measurement uncertainties.
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