Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Formula Mass and Mole Concepts of Compounds02:56

Formula Mass and Mole Concepts of Compounds

82.8K
Formula Mass of Covalent Compounds
82.8K
Balancing Redox Equations02:58

Balancing Redox Equations

62.7K
Electrochemistry is the science involved in the interconversion of electrical and chemical reactions. Such reactions are called reduction-oxidation, or redox reactions. These important reactions are defined by changes in oxidation states for one or more reactant elements and include a subset of reactions involving the transfer of electrons between reactant species. Electrochemistry as a field has evolved to yield sufficient insights on the fundamental principles of redox chemistry and multiple...
62.7K
Self-Concept01:19

Self-Concept

1.7K
Self-concept is the cognitive and emotional understanding individuals hold about their identity. It evolves through various developmental stages, beginning in infancy and maturing as children grow. This concept influences how individuals perceive their abilities, interact with others, and manage challenges throughout life.
Infancy and Emerging Recognition
During infancy, self-concept is virtually nonexistent. Babies do not distinguish themselves as separate entities and often mistake their...
1.7K
The Uncertainty Principle04:08

The Uncertainty Principle

33.2K
Werner Heisenberg considered the limits of how accurately one can measure properties of an electron or other microscopic particles. He determined that there is a fundamental limit to how accurately one can measure both a particle’s position and its momentum simultaneously. The more accurate the measurement of the momentum of a particle is known, the less accurate the position at that time is known and vice versa. This is what is now called the Heisenberg uncertainty principle. He...
33.2K
Hardy-Weinberg Principle01:49

Hardy-Weinberg Principle

76.7K
Diploid organisms have two alleles of each gene, one from each parent, in their somatic cells. Therefore, each individual contributes two alleles to the gene pool of the population. The gene pool of a population is the sum of every allele of all genes within that population and has some degree of variation. Genetic variation is typically expressed as a relative frequency, which is the percentage of the total population that has a given allele, genotype or phenotype.
76.7K
The Pauli Exclusion Principle03:06

The Pauli Exclusion Principle

59.6K
The arrangement of electrons in the orbitals of an atom is called its electron configuration. We describe an electron configuration with a symbol that contains three pieces of information:
59.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comprehensive evaluation of reference miRNA for extracellular miRNA quantification in CKD.

Methods (San Diego, Calif.)·2026
Same author

Response to the "Letter to the Editor: Prebiotic Administration to Chronic Kidney Disease Patients Modifies Their Microbiome and Metabolism".

Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation·2026
Same author

Four-organ SOFA score as a potential tool to triage use of continuous kidney replacement therapy in COVID-19 patients with acute kidney injury: a retrospective two-center study.

Renal failure·2026
Same author

Baseline Human Metabolic Profiling and Risk of Death from COVID-19: Conceptualization of Multivariate Prediction Model Development via Retrospective Database Analysis in the United States Department of Veterans Affairs.

Journal of clinical medicine·2026
Same author

New directions from the COMPASS study: A qualitative review of participation and communication in rural kidney health research.

BMC nephrology·2026
Same author

Can one use serum Lactate Concentration to Correct for the Anion gap?

Journal of intensive care medicine·2026

Related Experiment Video

Updated: Feb 15, 2026

Principles of Rodent Surgery for the New Surgeon
10:29

Principles of Rodent Surgery for the New Surgeon

Published on: January 6, 2011

117.6K

Fluid balance concepts in medicine: Principles and practice.

Maria-Eleni Roumelioti1, Robert H Glew2, Zeid J Khitan3

  • 1Division of Nephrology, Department of Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87131, United States.

World Journal of Nephrology
|January 24, 2018
PubMed
Summary

Body fluid balance involves tonicity, sodium balance, and extracellular volume. Effective arterial blood volume (EABV) is crucial for organ perfusion, but its assessment in severe illness is challenging and requires further research.

Keywords:
Body fluidsBody waterCongestive heart failureExtracellular volumeHepatic cirrhosisHypertonicityHypotonicityNephrotic syndromeSepsis

More Related Videos

Author Spotlight: Developing Low-Tech Balance Assessment Methods for Broad-Spectrum Healthcare Applications
06:28

Author Spotlight: Developing Low-Tech Balance Assessment Methods for Broad-Spectrum Healthcare Applications

Published on: September 1, 2023

6.3K
Assessment of Motor Balance and Coordination in Mice using the Balance Beam
07:03

Assessment of Motor Balance and Coordination in Mice using the Balance Beam

Published on: March 10, 2011

48.7K

Related Experiment Videos

Last Updated: Feb 15, 2026

Principles of Rodent Surgery for the New Surgeon
10:29

Principles of Rodent Surgery for the New Surgeon

Published on: January 6, 2011

117.6K
Author Spotlight: Developing Low-Tech Balance Assessment Methods for Broad-Spectrum Healthcare Applications
06:28

Author Spotlight: Developing Low-Tech Balance Assessment Methods for Broad-Spectrum Healthcare Applications

Published on: September 1, 2023

6.3K
Assessment of Motor Balance and Coordination in Mice using the Balance Beam
07:03

Assessment of Motor Balance and Coordination in Mice using the Balance Beam

Published on: March 10, 2011

48.7K

Area of Science:

  • Physiology
  • Nephrology
  • Critical Care Medicine

Background:

  • Body fluid balance is critical for health and disease, involving tonicity, sodium balance, and extracellular volume.
  • Tonicity disturbances affect cell volume, impacting brain function.
  • Effective arterial blood volume (EABV) ensures organ perfusion but is complex to assess.

Purpose of the Study:

  • To elucidate the three key concepts of body fluid balance regulation.
  • To highlight the challenges in measuring and managing extracellular volume in severe illness.
  • To propose extracellular volume in severe illness as a distinct concept.

Main Methods:

  • Conceptual analysis of body fluid regulation.
  • Review of factors influencing effective arterial blood volume (EABV).
  • Discussion of challenges in extracellular volume assessment in critical illness.

Main Results:

  • Body fluid balance is conceptualized into three distinct areas: tonicity, sodium balance/extracellular volume, and extracellular volume in severe illness.
  • Tonicity is determined by solutes distributed across body fluid compartments.
  • EABV regulation is multifactorial, and its assessment in severe illness is complex and error-prone.

Conclusions:

  • Understanding body fluid balance requires considering tonicity, sodium balance, and the unique challenges of extracellular volume in severe illness.
  • Accurate assessment and determination of optimal extracellular volume in critical illness remain significant challenges.
  • Further research is essential to define optimal extracellular volume targets for various severe illnesses.