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Published on: June 13, 2025
[Granulated Proctosigmoiditis by Antibiotic-associated Infection with Pseudomonas Aeruginosa]
Philipp Kapp1,2, Wolfgang Meier2, Roland Reinehr2
1Kreisklinik Groß-Umstadt.
History And Admission Findings:
We report on the case of an elderly patient with persisting diarrhea. Few weeks previous of admission the patient had received antibiotic therapy because of respiratory infection. On admission he seemed exsiccated and feeble.
Examinations:
Macroscopic findings in colonoscopy showed proctosigmoiditis and membranous exsudations. Stool culture provided the evidence for an antibiotic-associated infection with pseudomonas aeruginosa.
Treatment And Course:
The recommended oral therapy with ciprofloxacin proved to be effective.
Conclusion:
Complications with elderly patients are multimorbidity and diarrhea-induced prerenal failure. Frail patients can react strongly to antibiotic therapy with enteritis and dysbacteriosis.
Insights
Elderly patients experiencing persistent diarrhea after antibiotic treatment may have Clostridioides difficile infection. Prompt diagnosis and targeted therapy, such as with ciprofloxacin, are crucial for recovery.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Geriatrics
Background:
- Antibiotic therapy can disrupt the gut microbiome, leading to opportunistic infections.
- Elderly patients are particularly vulnerable to complications from dysbacteriosis.
Observation:
- A case of an elderly patient presenting with persistent diarrhea following antibiotic treatment for a respiratory infection.
- Colonoscopy revealed proctosigmoiditis with membranous exudations.
- Stool culture confirmed an antibiotic-associated infection caused by Pseudomonas aeruginosa.
Findings:
- Pseudomonas aeruginosa identified as the causative agent of antibiotic-associated diarrhea.
- Oral ciprofloxacin therapy demonstrated effectiveness in treating the infection.
Implications:
- Highlights the risk of antibiotic-associated infections in the elderly.
- Emphasizes the importance of considering dysbacteriosis and secondary infections in elderly patients with persistent diarrhea post-antibiotics.
- Ciprofloxacin can be an effective treatment option for Pseudomonas aeruginosa-induced enteritis.
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