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Chronic Hepatitis C Screening, Evaluation, and Treatment Update in the Age of Direct-Acting Antivirals

Miranda Surjadi1

  • 11 University of California, San Francisco.

Workplace Health & Safety
|January 24, 2018
PubMed

Insights

Hepatitis C virus (HCV) screening is recommended for all adults, presenting an opportunity for workplace outreach. Occupational health nurses can facilitate HCV testing and linkage to care, leveraging new curative treatments.

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Public Health

Background:

  • Hepatitis C virus (HCV) is a significant global health concern, affecting millions in the US, with many undiagnosed.
  • Workplace screening for bloodborne pathogens (BBP) typically occurs post-exposure, but broader HCV screening is less understood.
  • New CDC guidelines recommend universal HCV screening for individuals born between 1945-1965, irrespective of risk factors.

Purpose of the Study:

  • To review Hepatitis C virus (HCV) management in the era of direct-acting antivirals (DAAs).
  • To highlight the opportunity for workplace-based HCV outreach and screening.
  • To emphasize the role of occupational health nurses in HCV identification and care linkage.

Main Methods:

  • Review of current HCV epidemiology and diagnostic guidelines.
  • Analysis of the impact of direct-acting antiviral (DAA) therapies on HCV treatment.
  • Discussion of workplace strategies for HCV education, screening, and referral.

Main Results:

  • Direct-acting antivirals (DAAs) offer a cure for Hepatitis C virus (HCV).
  • Universal HCV screening recommendations create a new avenue for early detection.
  • Worksite interventions can increase HCV awareness and testing.

Conclusions:

  • Occupational health nurses are pivotal in identifying potential HCV-positive individuals within the workplace.
  • Worksite screening and education programs can improve HCV diagnosis rates.
  • Linking identified individuals to specialists ensures access to curative DAA treatment, reducing the HCV burden.

Keywords:
CDC guidelinesHCV screeningHCV treatmentdirect-acting antivirals (DAAs)occupational health nursing

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