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[Struma ovarii associated with Graves' disease].
Valeria Pastorino Casas1, M Florencia Borghi Torzillo1, Daniel Schere2
1Servicio de Endocrinología, Servicio de Endocrinología y Metabolismo, Complejo Médico Churruca-Visca, Buenos Aires, Argentina.
Medicina
|January 24, 2018
Summary
This study details a rare case of hyperthyroidism caused by struma ovarii co-occurring with Graves' disease. This highlights an uncommon but significant association in ectopic thyroid conditions.
Area of Science:
- Endocrinology
- Gynecologic Oncology
Background:
- Hyperthyroidism, excessive thyroid hormone production, affects 1.2% of the population.
- Graves' disease is the most frequent cause of hyperthyroidism.
- Struma ovarii, an ovarian teratoma containing thyroid tissue, is a rare cause of ectopic hyperthyroidism.
Observation:
- Struma ovarii constitutes 1% of ovarian tumors and is typically benign (>90%).
- Only 8% of struma ovarii cases present with thyrotoxicosis.
- The co-occurrence of struma ovarii and Graves' disease is exceptionally rare.
Findings:
- The case report describes a patient with the simultaneous presence of struma ovarii and Graves' disease.
- This association presents a diagnostic and therapeutic challenge in managing hyperthyroidism.
Implications:
- This case underscores the importance of considering ectopic thyroid tissue in hyperthyroid patients, even with common causes present.
- Further investigation into the pathogenesis and management of combined struma ovarii and Graves' disease is warranted.