Related Experiment Video

Updated: Feb 15, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.7K

The Adenoid Microbiome in Recurrent Acute Otitis Media and Obstructive Sleep Apnea

Carolyn O Dirain1, Rodrigo C Silva1, William O Collins1

  • 1Department of Otolaryngology, University of Florida, Gainesville, USA.

The Journal of International Advanced Otology
|January 24, 2018
PubMed
Abstract

Insights

Microbial differences exist on adenoids from children with recurrent acute otitis media (AOM) and obstructive sleep apnea (OSA). These distinct bacterial profiles may influence disease development, but their clinical significance requires further investigation.

Area of Science:

  • Microbiology
  • Otolaryngology
  • Genetics

Background:

  • Adenoids play a role in respiratory and immune health.
  • Recurrent acute otitis media (AOM) and obstructive sleep apnea (OSA) are common pediatric conditions often treated with adenoidectomy.
  • The microbial composition of adenoids in these conditions is not fully understood.

Purpose of the Study:

  • To compare the adenoid microbiome in children with recurrent AOM versus OSA.
  • To identify specific bacterial species associated with each condition.

Main Methods:

  • Prospective, controlled study involving adenoid tissue from children undergoing adenoidectomy.
  • DNA isolation and 16S DNA 454-pyrosequencing for microbial profiling.
  • Real-time PCR to quantify Streptococcus salivarius.

Main Results:

  • All adenoid samples harbored microbes, with common species including H. influenzae, M. catarrhalis, S. pneumoniae, P. aeruginosa, and S. aureus.
  • Specific bacteria like S. salivarius, Prevotella sp., and T. aromaticivorans were more prevalent in OSA patients.
  • Bradyrhizobium sp. was more common in recurrent AOM patients.
  • Microbial profiles differed between AOM and OSA groups, with some overlap.

Conclusions:

  • Adenoids host diverse microbial communities.
  • Distinct microbial profiles are associated with recurrent AOM and OSA in children.
  • The clinical implications of these adenoid microbiome differences warrant further research.

More Related Videos

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

1.5K
Multi-Modal Home Sleep Monitoring in Older Adults07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

8.3K

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
599
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
963
Stages of Sleep01:22

Stages of Sleep

Sleep progresses through distinct stages, each characterized by specific brain wave patterns and physiological responses ranging from wakefulness to stages of non-rapid eye movement, known as non-REM, to rapid eye movement, referred to as REM. Understanding these stages helps in recognizing how sleep supports various bodily and cognitive functions.
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
1.5K
Understanding Sleep01:11

Understanding Sleep

Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
1.6K
Sleepwalking and Sleep Talking01:17

Sleepwalking and Sleep Talking

Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
1.1K
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
463