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Prospective Study of Brain Wave Changes Associated With Cranial Electrotherapy Stimulation
R Gregory Lande1,2, Cynthia T Gragnani2
1Psychiatry Continuity Service, Behavioral Health Directorate, Walter Reed National Military Medical Center, 8901 Rockville Pike, Bethesda, MD 20889. Raymond.g.lande.civ@mail.mil.
The Primary Care Companion for CNS Disorders
|January 24, 2018
Summary
Cranial electrotherapy stimulation (CES) significantly increased beta brain waves, enhancing mental alertness and focus in psychiatric patients. These effects persisted and were more pronounced 10 minutes post-session, indicating sustained cognitive benefits.
Area of Science:
- Neuroscience
- Psychiatry
- Electroencephalography
Background:
- ClinicalTrials.gov identifier NCT03298308.
- Study conducted at Walter Reed National Military Medical Center's Psychiatry Continuity Service.
- Focus on active-duty military subjects receiving psychiatric care.
Purpose of the Study:
- To explore brain wave changes associated with cranial electrotherapy stimulation (CES).
- To assess the impact of CES on mental alertness, focus, and concentration in psychiatric patients.
Main Methods:
- Quantitative electroencephalogram (EEG) data collected before and after a 20-minute CES session.
- Fifty active-duty military subjects participated.
- Main outcome measures included changes in brain wave activity and Subjective Units of Distress Scale.
Main Results:
- Immediate post-CES: significant increase in higher beta frequencies (18-48 Hz) with a strong effect size (Cohen d ≈ 1.5).
- 10 minutes post-CES: significant decrease in slower wave activity (4-12 Hz) and sustained increase in beta wave activity (18-33 Hz).
- Typical subject presented with mild depression, severe trauma-related symptoms, and sleep disturbances.
Conclusions:
- CES significantly impacts brain wave activity, particularly in the beta region, immediately after a 20-minute session.
- The observed changes suggest increased mental alertness, focus, and concentration.
- Sustained cognitive benefits were noted 10 minutes post-CES, with reduced slow wave activity and persistent beta wave increases.
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