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Related Concept Videos

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

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Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
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Peritoneal Dialysis I: Introduction and Procedure01:30

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Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...
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Peritoneal Dialysis III: Nursing Management01:25

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Peritoneal dialysis, or PD, utilizes the peritoneal membrane as a filter to eliminate excess fluid and waste products. Effective nursing management is essential for ensuring patient safety, preventing complications, and promoting optimal function of the peritoneal dialysis process.Assessment and MonitoringNurses must thoroughly assess the patient before, during, and after each dialysis session. Regular monitoring includes vital signs, daily weight, fluid intake and output, and laboratory values...
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Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis01:30

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Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
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Dialysis01:27

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Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
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Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
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Updated: Feb 15, 2026

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
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Peritoneal dialysis beyond kidney failure?

Anna Pratsinis1, Olivier Devuyst2, Jean-Christophe Leroux1

  • 1Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland.

Journal of Controlled Release : Official Journal of the Controlled Release Society
|January 24, 2018
PubMed
Summary

Peritoneal dialysis (PD) offers a less invasive, cost-effective alternative to traditional methods. This review explores PD

Keywords:
AntidoteFormulationNanoparticlePeritoneal dialysis

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Area of Science:

  • Nephrology
  • Critical Care Medicine
  • Biomedical Engineering

Background:

  • Peritoneal dialysis (PD) is primarily used for end-stage renal failure.
  • PD offers a less invasive and more cost-effective approach compared to extracorporeal dialysis.
  • PD involves intra-corporeal blood dialysis against a peritoneal cavity solution.

Purpose of the Study:

  • To review the applications of peritoneal dialysis beyond kidney failure.
  • To explore established and emerging non-renal indications for PD.
  • To discuss future developments in PD technology and applications.

Main Methods:

  • Literature review of established and experimental PD applications.
  • Analysis of PD's role in various medical conditions.
  • Discussion of novel dialysate formulations and future research directions.

Main Results:

  • Established non-renal indications include hypothermia, congestive heart failure, hyperammonemia, and poisoning.
  • Historically relevant but unestablished indications include acute pancreatitis and psoriasis.
  • Emerging applications involve stroke management and oxygenation therapy using novel carriers.

Conclusions:

  • Peritoneal dialysis has diverse applications beyond renal replacement therapy.
  • Ongoing research focuses on advanced dialysates for enhanced detoxification and oxygenation.
  • Further characterization studies are needed for clinical translation of novel PD therapies.