[Specificity of carp antihuman myeloma protein sera depending on the holding temperature]

While in carps kept in warm water (28 degrees C) and immunized with a human myeloma protein a challenge leads to an increase, the antibody titres in carps kept in cold water (14 degrees C) are changed only unsignificantly. Antibody titres of carps immunized once respectively three times and kept in cold water are not markedly different. In testing the specificity of the antisera taken from each of the three groups no differences could be recognized. With carp anti-IgGZei sera using the passive hemagglutination inhibition test a paraprotein characterizing determinant (s) is just as well demonstrable as by using a rabbit antiserum.