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Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
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[Risk Assessment of Chemotherapy for the Elderly Patients with Gastrointestinal Cancer]
1Dept. of Gastroenterological Medical Oncology, Saitama Medical University International Medical Center.
Abstract:
The basic principles in the chemotherapeutic treatment of elderly colorectal cancer patients are similar to those of young people, but because of age-related organ function deterioration and comorbidities that are involved in life prognosis, there are risks of side effects in drug therapy. Considering the influence on the quality of life(QOL)is necessary. In the treatment guidelines, recommended initial chemotherapeutic options for unresectable colorectal cancer depends on whether the patient is appropriate for intensive therapy, but there are no criteria on how to divide. International Society of Geriatric Oncology (SIOG)recommend screening tool, i. e. G8, is recommended to identify those patients in need of comprehensive geriatric assessment(CGA). If abnormal, screening should be followed by CGA. Further researches are ongoing to build clinical pathways using screening tool and CGA.
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