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Updated: Feb 15, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
Comparison between Bilateral and Unilateral Sudden Sensorineural Hearing Loss.
Dan Bing1, Da-Yong Wang1, Lan Lan1
1Department of Otolaryngology-Head and Neck Surgery, Institute of Otolaryngology, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Bilateral sudden sensorineural hearing loss (BSSHL) is a rare subtype of sudden sensorineural hearing loss (SSHL). While not a distinct entity, BSSHL shows a higher rate of descending audiogram patterns and poorer hearing outcomes compared to unilateral SSHL.
Area of Science:
- Otolaryngology
- Audiology
- Internal Medicine
Background:
- Bilateral sudden sensorineural hearing loss (BSSHL) is rare and often considered distinct from unilateral SSHL (USSHL).
- This study investigates the clinical and audiological differences between idiopathic BSSHL and USSHL.
Purpose of the Study:
- To compare idiopathic BSSHL with USSHL in terms of patient demographics, clinical characteristics, and treatment outcomes.
- To determine if BSSHL represents a unique clinical entity or a variant of USSHL.
Main Methods:
- Retrospective analysis of 46 sequential BSSHL (Se-BSSHL) and 68 simultaneous BSSHL (Si-BSSHL) patients.
- Comparison with two control groups: USSHL with a healthy contralateral ear and USSHL with contralateral preexisting hearing loss (USSHLwCHL).
- Propensity score matching (PSM) was used to control for age, gender, and BMI, followed by statistical analysis (ANOVA, Kruskal-Wallis, Welch's t-test, Chi-square).
Main Results:
- Idiopathic BSSHL accounted for 8.6% of SSHL cases.
- USSHL patients were generally younger, female, with lower BMI, renal parameters, and cholesterol.
- After PSM, BSSHL patients showed similar hearing thresholds to USSHL but significantly better than USSHLwCHL. BSSHL exhibited a descending audiogram pattern and inferior hearing gain compared to USSHL.
Conclusions:
- Idiopathic BSSHL is a rare subtype of SSHL, not a completely separate disease entity from USSHL.
- BSSHL is characterized by a higher prevalence of descending audiogram patterns and less favorable hearing outcomes.
- These findings suggest BSSHL shares similarities with USSHL but has distinct audiological characteristics and prognosis.
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