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fMRI Mapping of Brain Activity Associated with the Vocal Production of Consonant and Dissonant Intervals

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Published on: May 23, 2017

Infantile myofibromatosis.

Margarita Larralde^1,2, Bruno Ferrari¹, Juan Pablo Martinez¹

¹Pediatric Dermatology Section, Hospital Ramos Mejía, Buenos Aires, Argentina.

Anais Brasileiros De Dermatologia

|January 25, 2018

Summary

Infantile myofibromatosis, a common childhood fibrous tumor, can affect skin and bone. A newborn with this condition responded well to vinblastine and methotrexate treatment.

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Area of Science:

Pediatric Oncology
Dermatopathology
Skeletal Dysplasias

Background:

Infantile myofibromatosis is the most common fibrous tumor in childhood.
It is a mesenchymal disorder involving fibrous proliferation in various tissues.
This condition can manifest in the skin, bone, muscle, and viscera.

Observation:

A case report of a newborn presenting with infantile myofibromatosis.
The newborn exhibited involvement of the skin and bone.
Importantly, there was no visceral organ involvement.

Findings:

The newborn demonstrated a positive therapeutic response to a combination of vinblastine and methotrexate.
This suggests potential efficacy of chemotherapy in specific presentations of infantile myofibromatosis.
The case highlights a non-visceral form of the disease.

Implications:

This case contributes to understanding the clinical spectrum of infantile myofibromatosis.
It underscores the importance of considering chemotherapy in managing non-visceral infantile myofibromatosis.
Further research into targeted therapies for infantile myofibromatosis is warranted.